Our knowledge regarding the molecular basis of muscle spindle function is still incomplete.
However, increasing our understanding of mechanotransduction in muscle spindles is a …

Key points Locomotion on land and in water requires the coordination of a great number of
muscle activations and joint movements. Constant feedback about the position of own body …

Proprioception, the perception of body and limb position, is mediated by proprioceptors,
specialized mechanosensory neurons that convey information about the stretch and tension …

The somatosensory nervous system is subserved by specialised mechanoreceptors in
muscles, joints and skin. We now know that joint receptors primarily act as limit detectors of …

Animals rely on an internal sense of body position and movement to effectively control motor
behavior. This sense of proprioception is mediated by diverse populations of …

Proprioception, the sense of limb position and motion, arises from individual muscle
receptors. An important question is how and where in the neuroaxis our high level “extrinsic” …

Somatosensory inputs can be grossly divided into tactile (or cutaneous) and proprioceptive--
the former conveying information about skin stimulation, the latter about limb position and …

Relay of muscle-derived sensory information to the CNS is essential for the execution of
motor behavior, but how proprioceptive sensory neurons (pSNs) establish functionally …

Proprioception, the sense of self-movement and position, is mediated by mechanosensory
neurons that detect diverse features of body kinematics. Although proprioceptive feedback is …

Muscle spindles, one of the two main classes of proprioceptors together with Golgi tendon
organs, are sensory structures that keep the central nervous system updated about the …