DHEAS and cortisol/DHEAS-ratio in recurrent depression: state, or trait predicting 10-year recurrence?

RJT Mocking, CM Pellikaan, A Lok, J Assies… - …, 2015 - Elsevier
Background Major depressive disorder (MDD) has been associated with low
dehydroepiandrosterone-sulphate (DHEAS),–particularly relative to high cortisol–although …

Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression

CM Hough, D Lindqvist, ES Epel, MS Denis… - …, 2017 - Elsevier
Background Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-
S),(together DHEA [S]), are the most abundant adrenal steroids in humans and are found in …

Cortisol and changes in depressive symptoms: The moderating role of DHEA

SN Doan, AS Davis, TE Fuller-Rowell - Psychoneuroendocrinology, 2024 - Elsevier
Stress is associated with activation of the hypothalamus-adrenal-axis (HPA). Cortisol, a
product of the HPA, is thought to predict depression. However, to date, the majority of studies …

Difference in pre-and post-treatment plasma DHEA levels were significantly and positively correlated with difference in pre-and post-treatment Hamilton depression …

CC Hsiao - Psychoneuroendocrinology, 2006 - Elsevier
OBJECTIVE: Clinical studies of endogenous concentrations of dehydroepiandrosterone
(DHEA) and its relation to depression are limited. This study examined whether pre-and post …

[HTML][HTML] Higher serum dehydroepiandrosterone sulfate protects against the onset of depression in the elderly: findings from the English Longitudinal Study of Aging …

LH Souza-Teodoro, C de Oliveira, K Walters… - …, 2016 - Elsevier
Depression is one of the major causes of disability worldwide, but the complete etiology of
depression is not fully understood. Dehydroepiandrosterone (DHEA) and its sulphated form …

Cortisol, dehydroepiandrosterone sulfate, fatty acids, and their relation in recurrent depression

DM Ter Horst, AH Schene, CA Figueroa… - …, 2019 - Elsevier
Background Alterations in hypothalamic–pituitary–adrenal (HPA)-axis activity, fatty acid
metabolism, and their relation have been associated with (recurrent) major depressive …

Attenuated DHEA and DHEA-S response to acute psychosocial stress in individuals with depressive disorders

X Jiang, W Zhong, H An, M Fu, Y Chen, Z Zhang… - Journal of Affective …, 2017 - Elsevier
Background In recent years, a relationship between depression and basal
dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) levels has …

Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants

T Morita, K Senzaki, R Ishihara… - Human …, 2014 - Wiley Online Library
Objective We attempted to investigate whether dehydroepiandrosterone sulfate (DHEA‐S)
levels are associated with remission of major depressive disorder by assessing scores on …

The ratio of cortisol/DHEA in treatment resistant depression

K Markopoulou, A Papadopoulos, MF Juruena… - …, 2009 - Elsevier
OBJECTIVE: Hypercortisolaemia has been well described in depression and may be a
factor associated with treatment resistance. The role of the more abundant adrenal steroid …

Serum dehydroepiandrosterone sulfate and incident depression in the elderly: the Pro. VA study

N Veronese, M De Rui, F Bolzetta, S Zambon… - The American Journal of …, 2015 - Elsevier
Objective Dehydroepiandrosterone sulfate (DHEAS) appears to have a protective effect
against depression, but contrasting findings are available. Therefore, we investigated …