Molnupiravir for SARS-CoV-2 infection: Public health and policy implications

EJ Gray, JS Nguyen-Van-Tam - Journal of Infection, 2023 - journalofinfection.com
This has been the fastest recruiting clinical trial ever in the UK, and a testament to the
combined research capability of the National Health Service (NHS), National Institute for …

[HTML][HTML] Hospitalization among patients treated with molnupiravir: A retrospective study of administrative data

G Prajapati, A Das, Y Sun, E Fonseca - Clinical Therapeutics, 2023 - Elsevier
Purpose Molnupiravir is an oral antiviral agent authorized for emergency use to treat mild to
moderate cases of coronavirus disease 2019 (COVID-19) in adults at high risk for …

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

WA Fischer, JJ Eron Jr, W Holman, MS Cohen… - Science translational …, 2021 - science.org
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …

Effectiveness of molnupiravir vs nirmatrelvir-ritonavir in non-hospitalised and hospitalised patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, ZCT Wong, CSL Chui… - …, 2023 - thelancet.com
Background Molnupiravir and nirmatrelvir-ritonavir have emerged as promising options for
COVID-19 treatment, but direct comparisons of their effectiveness have been limited. This …

Role of Molnupiravir in the Treatment of COVID-19

A Sharma, VM Patil, M Dahiya, GP Singh… - Anti-Infective …, 2023 - ingentaconnect.com
Background: Molnupiravir is a ribonucleoside analog and exhibits its antiviral mechanism by
inhibiting replication. Preclinical studies have been reported that support the role of …

A mini-review on clinical studies of Molnupiravir for COVID-19 conducted in selected Asian countries

JMB Querequincia, EM Faller - GSC Biological and …, 2022 - gsconlinepress.com
The key goal of this mini review article is to provide enough data and info on the several
clinical trials conducted in some number of countries in the Asia on the use of the drug …

[HTML][HTML] Evaluation of publication bias for 12 clinical trials of molnupiravir to treat SARS-CoV-2 infection in 13,694 patients

J Lawrence, M Mirchandani, A Hill - 2022 - europepmc.org
Methods Searches of the Clinical Trials Registry-India (CTRI) were conducted to find
registered trials of molnupiravir in India. Subsequent investigations were performed to …

Molnupiravir: A new candidate for COVID‐19 treatment

F Pourkarim, S Pourtaghi‐Anvarian… - Pharmacology …, 2022 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) emerged in late December 2019 in china
and has rapidly spread to many countries around the world. The effective pharmacotherapy …

Molnupiravir and risk of hospital admission or death in adults with covid-19: emulation of a randomized target trial using electronic health records

Y Xie, B Bowe, Z Al-Aly - bmj, 2023 - bmj.com
Objective To emulate a randomized target trial to estimate the association between the
antiviral drug molnupiravir and hospital admission or death in adults with SARS-CoV-2 …

Impact of molnupiravir treatment on patient-reported COVID-19 symptoms in the phase 3 MOVe-OUT trial: a randomized, placebo-controlled trial

Y Guan, A Puenpatom, MG Johnson… - Clinical Infectious …, 2023 - academic.oup.com
Background Molnupiravir is an orally administered antiviral authorized for COVID-19
treatment in adults at high risk of progression to severe disease. Here, we report secondary …