The continuous population increase of older adults with metabolic diseases may contribute
to increased prevalence of sarcopenia and obesity and requires advocacy of optimal …

Background Anorexia of ageing is common and important in the development of sarcopenia
in older individuals. Links have been proposed between the gut microbiota and sarcopenia …

Skeletal muscle mass plays a critical role in a healthy lifespan by helping to regulate
glucose homeostasis. As seen in sarcopenia, decreased skeletal muscle mass impairs …

Aging is associated with a decline in skeletal muscle mass and function—termed sarcopenia—
as mediated, in part, by muscle anabolic resistance. This metabolic phenomenon describes …

Inadequate nutrition and physical inactivity are the mainstays of primary sarcopenia–
physiopathology in older individuals. Gut microbiota composition is strongly dependent on …

Background and aims Despite animal studies revealing a causal link between the gut
microbiota and skeletal muscle mass, the role of the gut microbiome and its metabolites in …

Human gut microbiota is able to influence the host physiology by regulating multiple
processes, including nutrient absorption, inflammation, oxidative stress, immune function …

Abstract 16S rRNA sequencing of human fecal samples has been tremendously successful
in identifying microbiome changes associated with both aging and disease. A number of …

The gut microbiota could influence the pathophysiology of age-related sarcopenia through
multiple mechanisms implying modulation of chronic inflammation and anabolic resistance …

Muscle mass, strength, and physical function are known to decline with age. This is
associated with the development of geriatric syndromes including sarcopenia and frailty …