MRI markers for mild cognitive impairment: comparisons between white matter integrity and gray matter volume measurements

Y Zhang, N Schuff, M Camacho, LL Chao, TP Fletcher… - PloS one, 2013 - journals.plos.org
The aim of the study was to evaluate the value of assessing white matter integrity using
diffusion tensor imaging (DTI) for classification of mild cognitive impairment (MCI) and …

Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor …

L Wang, FC Goldstein, E Veledar… - American journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Mild cognitive impairment (MCI) is a risk factor for
Alzheimer disease and can be difficult to diagnose because of the subtlety of symptoms …

Diffusion tensor imaging measures of normal appearing white matter in patients who are aging, or have amnestic mild cognitive impairment, or Alzheimer's disease

JH Wang, PY Lv, HB Wang, ZL Li, N Li, ZY Sun… - Journal of Clinical …, 2013 - Elsevier
To evaluate whether cerebral white matter integrity is related to cognitive function, and
whether diffusion tensor imaging (DTI) could differentiate amnestic mild cognitive …

White matter integrity in mild cognitive impairment: a tract-based spatial statistics study

L Zhuang, W Wen, W Zhu, J Trollor, N Kochan… - Neuroimage, 2010 - Elsevier
Mild cognitive impairment (MCI) as a clinical diagnosis has limited specificity, and identifying
imaging biomarkers may improve its predictive validity as a pre-dementia syndrome. This …

Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study

A Fellgiebel, P Wille, MJ Müller, G Winterer… - Dementia and geriatric …, 2004 - karger.com
Mild cognitive impairment (MCI) is considered to be a transitional stage between normal
aging and dementia. In Alzheimer's disease (AD), white matter structural pathology is due to …

Diffusion tensor imaging (DTI) in the detection of white matter lesions in patients with mild cognitive impairment (MCI)

S Dimitra, DA Verganelakis, E Gotsis, P Toulas… - Acta Neurologica …, 2013 - Springer
Mild cognitive impairment (MCI) is recognized as a precursor to dementia. The amnestic MCI
progresses usually to Alzheimer disease. Amnestic MCI multiple domain (md-MCI) seems to …

White matter integrity and key structures affected in Alzheimer's disease characterized by diffusion tensor imaging

D Xiao, K Wang, L Theriault, E Charbel… - European Journal of …, 2022 - Wiley Online Library
White matter (WM) degeneration is suggested to predict the early signs of Alzheimer's
disease (AD). The exact structural regions of brain circuitry involved are not known. This …

Diffusion tensor imaging in Alzheimer's disease and mild cognitive impairment

GT Stebbins, CM Murphy - Behavioural neurology, 2009 - content.iospress.com
Structural magnetic resonance imaging (MRI) studies of Alzheimer's disease and mild
cognitive impairment (MCI) have focused on the hippocampus and entorhinal cortex; gray …

Individual prediction of cognitive decline in mild cognitive impairment using support vector machine-based analysis of diffusion tensor imaging data

S Haller, D Nguyen, C Rodriguez… - Journal of …, 2010 - content.iospress.com
Although cross-sectional diffusion tensor imaging (DTI) studies revealed significant white
matter changes in mild cognitive impairment (MCI), the utility of this technique in predicting …

Cognitive impairment in MS: impact of white matter integrity, gray matter volume, and lesions

HE Hulst, MD Steenwijk, A Versteeg, PJW Pouwels… - Neurology, 2013 - AAN Enterprises
Objective: To investigate whether extent and severity of white matter (WM) damage, as
measured with diffusion tensor imaging (DTI), can distinguish cognitively preserved (CP) …