Columnar epithelium-lined esophagus (Barrett's esophagus) is an acquired disorder
associated with a high incidence of adenocarcinoma of the lower esophagus. Columnar …

Aims: To study the expression of MUC1 and MUC4 mucins in Barrett-associated
oesophageal adenocarcinoma and coexisting lesions of the carcinogenic sequence (normal …

BACKGROUND AND AIMS Mucin genes are expressed in a site specific manner throughout
the gastrointestinal tract. Little is known about the expression pattern in the oesophagus. In …

Results PAS-alcian blue and Mucin-2 were positive in all cases. Mucin expression was
positive in goblet cells and few columnar cells. PAS-alcian blue showed heterogeneous …

BACKGROUND: The molecular events that accompany the progression to adenocarcinoma
(ADC) of the esophagus are poorly understood. Aberrant mucin receptor expression can …

Introduction: Esophageal adenocarcinoma (EAC) has a poor 5-year survival rate (10%–
18%), and incidence has increased dramatically in the past three decades. Barrett's …

Objective: Despite widespread use of proton pump inhibitors (PPIs), the incidence of
esophageal adenocarcinoma (EAC) continues to rise. PPIs reduce reflux acidity, but only …

Objective To obtain biochemical evidence that Barrett's esophagus (BE) is the precursor of
most adenocarcinomas (Adc) of the esophagus and cardia. Summary Background Data …

Esophageal adenocarcinoma (EAC) is thought to develop from asymptomatic Barrett's
esophagus (BE) with a low annual rate of conversion. Current endoscopy surveillance of BE …

Barrett's mucosa is a potentially premalignant columnar lined metaplastic epithelium in the
oesophagus about which little is known regarding maintenance of cell adhesion. In this …