Epithelial-to-mesenchymal transition (EMT) has been closely linked with therapy resistance
and cancer stem cells (CSCs). However, EMT pathways have proven challenging to …

This study aimed to elucidate how miR-27a-3p modulates the Wnt/β-catenin signaling
pathway to promote colorectal cancer (CRC) progression. Our results showed that the …

Background Recent studies have reported that microRNAs (miRNAs) often function as
negative post-transcriptional regulators with altered expression levels found in colorectal …

Gene amplification is a hallmark of cancer and is frequently observed in colorectal cancer.
Previous whole-genome sequencing of colorectal cancer clinical specimens identified …

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal
cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and …

Abstract Background/Aims: The colorectal neoplasia differentially expressed (CRNDE) gene
is a long noncoding RNA (lncRNAs) that is upregulated in colorectal cancer and glioma …

Long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis and progression of
colorectal cancer (CRC). However, functions of most lncRNAs in CRC and their molecular …

Long noncoding RNAs (lncRNAs) have been indicated as important regulators in various
human cancers. However, the overall biological roles and clinical significance of most …

Background The function of a new long non-coding RNA linc00673 remains unclear. While
identified as an oncogenic player in non-small cell lung cancer (NSCLC), linc00673 was …

Cancer stemness drives tumor initiation, progression, metastasis, recurrence, and therapy
resistance. However, mechanisms that potentiate the acquisition and maintenance of …