Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

V Stalin Raj, NMA Okba, J Gutierrez-Alvarez… - Science …, 2018 - science.org
Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in
humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV …

Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine

LM Weskamm, A Fathi, MP Raadsen, AZ Mykytyn… - Cell Reports …, 2022 - cell.com
Summary The Middle East respiratory syndrome (MERS) is a respiratory disease caused by
MERS coronavirus (MERS-CoV). In follow up to a phase 1 trial, we perform a longitudinal …

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

AS Cockrell, BL Yount, T Scobey, K Jensen… - Nature …, 2016 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel virus that emerged in
2012, causing acute respiratory distress syndrome (ARDS), severe pneumonia-like …

A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine

C Hörner, C Schürmann, A Auste… - Proceedings of the …, 2020 - National Acad Sciences
The COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) and has spread worldwide, with millions of cases and more than 1 million …

Countrywide survey for MERS-coronavirus antibodies in dromedaries and humans in Pakistan

A Zohaib, M Saqib, MA Athar, J Chen, AR Sial, S Khan… - Virologica Sinica, 2018 - Springer
Abstract Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic
pathogen capable of causing severe respiratory disease in humans. Although dromedary …

Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels

RQ Liu, JY Ge, JL Wang, S Yu, HL Zhang… - Journal of integrative …, 2017 - Elsevier
Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae
family, is the causative pathogen for MERS that is characterized by high fever, pneumonia …

Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model

VJ Munster, D Wells, T Lambe, D Wright, RJ Fischer… - npj Vaccines, 2017 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic virus that
causes severe respiratory disease in humans with a case fatality rate close to 40%, but for …

Subunit vaccines against emerging pathogenic human coronaviruses

N Wang, J Shang, S Jiang, L Du - Frontiers in microbiology, 2020 - frontiersin.org
Seven coronaviruses (CoVs) have been isolated from humans so far. Among them, three
emerging pathogenic CoVs, including severe acute respiratory syndrome coronavirus …

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

D Corti, J Zhao, M Pedotti, L Simonelli… - Proceedings of the …, 2015 - National Acad Sciences
Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by
a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels …

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

XC Tang, SS Agnihothram, Y Jiao… - Proceedings of the …, 2014 - National Acad Sciences
The newly emerging Middle East Respiratory Syndrome coronavirus (MERS-CoV) causes a
Severe Acute Respiratory Syndrome-like disease with∼ 43% mortality. Given the recent …