Unresolved questions in the zoonotic transmission of MERS

M Peiris, S Perlman - Current opinion in virology, 2022 - Elsevier
The Middle East Respiratory Syndrome-coronavirus (MERS-CoV) is the second of three
zoonotic coronaviruses to infect humans since 2002, causing severe pneumonia. Unlike …

Molecular pathogenesis of middle east respiratory syndrome (MERS) coronavirus

A Banerjee, K Baid, K Mossman - Current Clinical Microbiology Reports, 2019 - Springer
Abstract Purpose of Review Middle East respiratory syndrome coronavirus (MERS-CoV)
emerged in 2012 and is listed in the World Health Organization's blueprint of priority …

[HTML][HTML] MERS-coronavirus: From discovery to intervention

W Widagdo, NMA Okba, VS Raj, BL Haagmans - One Health, 2017 - Elsevier
Middle East respiratory syndrome coronavirus (MERS-CoV) still causes outbreaks despite
public awareness and implementation of health care measures, such as rapid viral …

Development of Middle East respiratory syndrome coronavirus vaccines–advances and challenges

H Cho, JL Excler, JH Kim, IK Yoon - Human Vaccines & …, 2018 - Taylor & Francis
ABSTRACT Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an emerging
pathogen with the potential to pose a threat to global public health. Sporadic cases and …

[HTML][HTML] MERS-CoV vaccine candidates in development: The current landscape

K Modjarrad - Vaccine, 2016 - Elsevier
Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging infectious disease
of growing global importance, has caused severe acute respiratory disease in more than …

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

T Ying, P Prabakaran, L Du, W Shi, Y Feng… - Nature …, 2015 - nature.com
The MERS-CoV is an emerging virus, which already infected more than 1,300 humans with
high (∼ 36%) mortality. Here, we show that m336, an exceptionally potent human anti …

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on the Middle East respiratory syndrome coronavirus spike glycoprotein to avoid …

L Wang, W Shi, JD Chappell, MG Joyce… - Journal of …, 2018 - Am Soc Microbiol
Middle East respiratory syndrome coronavirus (MERS-CoV) causes a highly lethal
pulmonary infection with∼ 35% mortality. The potential for a future pandemic originating …

Stabilized coronavirus spike stem elicits a broadly protective antibody

CL Hsieh, AP Werner, SR Leist, LJ Stevens, E Falconer… - Cell reports, 2021 - cell.com
Current coronavirus (CoV) vaccines primarily target immunodominant epitopes in the S1
subunit, which are poorly conserved and susceptible to escape mutations, thus threatening …

Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development

E Kim, G Erdos, S Huang, TW Kenniston, SC Balmert… - …, 2020 - thelancet.com
Background Coronaviruses pose a serious threat to global health as evidenced by Severe
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and …

Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary …

RA Perera, P Wang, MR Gomaa… - …, 2013 - eurosurveillance.org
We describe a novel spike pseudoparticle neutralisation assay (ppNT) for
seroepidemiological studies on Middle East respiratory syndrome coronavirus (MERS-CoV) …