Medicinal fungi, including mushrooms, have well-documented therapeutic uses. In this
study, we perform a cheminformatics-based investigation of the scaffold and structural …

Fungi are a rich source of secondary metabolites which constitutes a valuable and diverse
chemical space of natural products. Medicinal fungi have been used in traditional medicine …

Many drug discovery projects rely on commercial compounds to discover active leads.
However, current commercial libraries, with mostly synthetic compounds, access a small …

Biological species collections are critical for natural product drug discovery programs.
However, prioritization of target species in massive collections remains difficult. Here, we …

Introduction Fungi biosynthesize chemically diverse secondary metabolites with a wide
range of biological activities. Natural product scientists have increasingly turned towards …

Covering: up to July 2020 Fungal metabolites with diverse and novel scaffolds can be
assembled from well-known biosynthetic precursors through various mechanisms. Recent …

Fungi are rich, underexploited reservoirs for natural products that may serve as medicines,
commodity chemicals, insecticides, pesticides and other valuable chemicals. Moreover, the …

Secondary metabolites synthesized by fungi have become a precious source of inspiration
for the design of novel drugs. Indeed, fungi are prolific producers of fascinating, diverse …

Filamentous fungi possess great potential as sources of medicinal bioactive compounds,
such as antibiotics, but efficient production is hampered by a limited understanding of how …

Aim: Fungi are valuable resources for bioactive secondary metabolites. However, the
chemical space of fungal secondary metabolites has been studied only on a limited basis …