The discovery and initial description of the interferon-λ (IFN-λ) family in early 2003 opened
an exciting new chapter in the field of IFN research. There are 3 IFN-λ genes that encode 3 …

The discovery of the interferon‐lambda (IFN‐λ) family has considerably contributed to our
understanding of the role of interferon not only in viral infections but also in cancer. IFN‐λ …

Type III interferon (IFN) or IFN-λ is a recently discovered family of IFNs that signal through
the same downstream transcription factors as type I IFN but use a separate receptor complex …

Interferon-λ (IFN-λ) is an antiviral cytokine that signals through a distinct receptor complex,
composed of the IFN-λR1 and interleukin-10R2 (IL-10R2) receptor chains. We have …

Type III interferons (IFNs)(interleukin-28/29 or lambda interferon [IFN-λ]) are cytokines with
IFN-like activities. Here we show that several classes of viruses induce expression of IFN-λ1 …

The interferon lambda family (IFN-λ1/2/3) is a newly described group of cytokines that are
related to both the type-1 interferons and IL-10 family members. These novel cytokines are …

The first line of defense against viral infections is mediated by interferons (IFN) s, which are
produced rapidly by the infected host. Type I IFNs (IFN-α/β) are known to combat viruses …

Recent findings concerning the biology of IFN-λs and their pathophysiological roles in viral
infection, cancer, and immune responses of the innate and adaptive arms are summarized …

IL-28 and IL-29 were recently described as members of a new cytokine family that shares
with type I interferon (IFN) the same Jak/Stat signalling pathway driving expression of a …

Interferons (IFN) exert antiviral, immunomodulatory and cytostatic activities. IFN-α/β (type I
IFN) and IFN-λ (type III IFN) bind distinct receptors, but regulate similar sets of genes and …