Identification of Helicobacter pylori and the cagA genotype in gastric biopsies using highly sensitive real-time PCR as a new diagnostic tool

S Yamazaki, S Kato, N Matsukura… - FEMS Immunology & …, 2005 - academic.oup.com
The CagA protein is one of the virulence factors of Helicobacter pylori, and two major
subtypes of CagA have been observed, the Western and East Asian type. CagA is injected …

Evaluation of Mutations in 23S rRNA, rdxA and frxA Genes of Helicobacter pylori in Paraffin-Embedded Gastric Biopsy Specimens from Iranian Gastric Cancer and …

S Beheshtirouy, S Eyvazi, V Tarhriz - Journal of Gastrointestinal Cancer, 2021 - Springer
Purpose Helicobacter pylori (H. pylori) infection is considered as one of the main cause of
gastric cancer. Treatment failure of the infection often occurs due to antibiotic resistance …

[PDF][PDF] Diagnostic accuracy of PCR based method using four gene primers to detect Helicobacter pylori infection in gastric tissues: Report from Iran

H Khedmat, A Karami, Z Safiri, M Amini… - Trop …, 2010 - eprints.bmsu.ac.ir
Precise detection of H. pylori infection is relevant for clinical practice as well as for research
purposes, and several invasive and noninvasive tests are currently available for diagnosis of …

Change in Diagnosis of Helicobacter pylori Infection in the Treatment-Failure Era

R Spagnuolo, GGM Scarlata, MR Paravati, L Abenavoli… - Antibiotics, 2024 - mdpi.com
Helicobacter pylori (H. pylori) infection is a prevalent global health issue, associated with
several gastrointestinal disorders, including gastritis, peptic ulcers, and gastric cancer. The …

Comparison of Genotyping Helicobacter pylori Directly from Biopsy Specimens and Genotyping from Bacterial Cultures

CY Park, M Kwak, O Gutierrez… - Journal of clinical …, 2003 - Am Soc Microbiol
ABSTRACT PCR for vacA and cagA genotypes of Helicobacter pylori using DNA isolated
from infected gastric biopsy specimens was approximately equal to genotyping using …

Nested-Polymerase Chain Reaction for the Detection ofHelicobacter pyloriInfection with Novel Primers Designed by Sequence Analysis of Urease A Gene in Clinically …

O Kawamata, H Yoshida, K Hirota, A Yoshida… - Biochemical and …, 1996 - Elsevier
We have established a highly sensitive semi-nested PCR assay for the detection ofH.
pyloriinfection using gastric juice samples, which can be aspirated with disposable …

Molecular fingerprinting of Helicobacter pylori strains from duodenal ulcer patients

L Cellini, E Di Campli, M Di Candia… - Letters in applied …, 2003 - academic.oup.com
Aims: To characterize the molecular fingerprinting of Helicobacter pylori population isolated
in duodenal ulcer patients treated with triple therapy. Methods and Results: Gastric biopsy …

Clarithromycin-Susceptible But Virulent Helicobacter pylori Strains Infecting Iranian Patients' Stomachs

S Khani, A Talebi Bezmin Abadi… - Infection and Drug …, 2019 - Taylor & Francis
Introduction Helicobacter pylori was discovered first in the stomachs of patients with gastritis
and ulcers by Marshall and Warren in 1982. This discovery majorly affected many research …

Droplet digital PCR-based detection of clarithromycin resistance in Helicobacter pylori isolates reveals frequent heteroresistance

L Sun, S Talarico, L Yao, L He, S Self… - Journal of clinical …, 2018 - Am Soc Microbiol
Chronic infection with Helicobacter pylori causes peptic ulcers and stomach cancer in a
subset of infected individuals. While standard eradication therapy includes multiple …

Unreliability of Results of PCR Detection of Helicobacter pylori in Clinical or Environmental Samples

M Sugimoto, JY Wu, S Abudayyeh… - Journal of clinical …, 2009 - Am Soc Microbiol
The aim of this study was to compare published Helicobacter pylori primer pairs for their
ability to reliably detect H. pylori in gastric biopsy specimens and salivary samples …