[HTML][HTML] The impact of obesity and sexual behavior on prostate cancer risk is mediated by testosterone levels: a mendelian randomization study and mediation …

H Di, Y Wen, J Wang, J Wang, Y Wang, Y Li, F Sun - Prostate International, 2024 - Elsevier
Background The relationship between obesity, sexual behavior, and prostate cancer (PCa)
has been widely debated, contributing to a lack of understanding of its potential mechanisms …

Do Obesity-Related Traits Affect Prostate Cancer Risk through Serum Testosterone? A Mendelian Randomization Study

C Yuan, Z Jian, S Feng, M Wang, L Xiang, H Li, X Jin… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is one of the most commonly diagnosed hormone-related
malignancies worldwide. Previous studies have suggested that an increased BMI is …

The relationship between metabolic syndrome components and prostate cancer risk: a Mendelian randomization study

C Shen, Z Zhu, X Zhang, M Fang, J Chen, F Shao… - 2024 - researchsquare.com
Purpose Numerous epidemiological studies have explored the association between the
components of metabolic syndrome (MetS) and risk of prostate cancer (PCa). However, to …

Interactions of obesity, body shape, diabetes and sex steroids with respect to prostate cancer risk in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - Cancer …, 2024 - Wiley Online Library
Background Obesity and diabetes are associated inversely with low‐grade prostate cancer
risk and affect steroid hormone synthesis but whether they modify each other's impact on …

Association of obesity and diabetes with prostate cancer risk groups in a multiethnic population

D Zhu, M Toker, W Shyr, E Fram, KL Watts… - Clinical Genitourinary …, 2022 - Elsevier
Introduction Obesity and diabetes mellitus (DM) have been associated with prostate cancer
(PCa) risk, but data examining their combined effects on aggressive PCa are sparse …

Pleiotropy between genetic markers of obesity and risk of prostate cancer

TL Edwards, A Giri, S Motley, W Duong… - … , biomarkers & prevention, 2013 - AACR
Background: To address inconsistent findings of obesity and prostate cancer risk, we
analyzed the association between prostate cancer and genetic markers of obesity and …

[HTML][HTML] Predicted body fat percentage, fat mass and lean body mass in relation to risk of prostate cancer: Results from the NHANES 1999 to 2010

S Wu, Q Zou, C Li, H Huang, Z Xiong - Medicine, 2024 - journals.lww.com
The purpose of this study is to examine the relationship between fat mass (FM), body fat
percentage (BF%), lean body mass (LM), and prostate cancer (PCa), and evaluate their …

Association between body mass index and prostate cancer among African American men

MS Pichardo, CJ Smith, W Tang, T Dorsey, S Ambs - Cancer Research, 2017 - AACR
Prostate cancer (PCa) is a leading cause of cancer death in US men. Yet, the etiology of
prostate cancer remains poorly understood, with only older age, African ancestry, family …

Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study

YB Wang, L Yang, YQ Deng, SY Yan, LS Luo… - Journal of translational …, 2022 - Springer
Background Obesity (waist circumference, body mass index (BMI)) and lifestyle factors
(dietary habits, smoking, alcohol drinking, Sedentary behavior) have been associated with …

Obesity and prostate cancer: weighing the evidence

EH Allott, EM Masko, SJ Freedland - European urology, 2013 - Elsevier
CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …