Electrical stimulation of denervated rat skeletal muscle retards capillary and muscle loss in early stages of disuse atrophy

K Nakagawa, H Tamaki, K Hayao… - BioMed Research …, 2017 - Wiley Online Library
The purpose of the present study is to investigate the effects of low‐frequency electrical
muscle stimulation (ES) on the decrease in muscle mass, fiber size, capillary supply, and …

[HTML][HTML] Low-frequency electrical stimulation of denervated skeletal muscle retards muscle and trabecular bone loss in aged rats

H Tamaki, K Yotani, F Ogita, K Hayao… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
Electrical stimulation (ES)-induced muscle contraction has multiple effects; however,
mechano-responsiveness of bone tissue declines with age. Here, we investigated whether …

Electrical stimulation of denervated rat skeletal muscle ameliorates bone fragility and muscle loss in early-stage disuse musculoskeletal atrophy

H Tamaki, K Yotani, F Ogita, K Hayao… - Calcified tissue …, 2017 - Springer
We tested whether daily muscle electrical stimulation (ES) can ameliorate the decrease in
cortical bone strength as well as muscle and bone geometric and material properties in the …

Low-intensity electrical stimulation ameliorates disruption of transverse tubules and neuromuscular junctional architecture in denervated rat skeletal muscle fibers

K Tomori, Y Ohta, T Nishizawa, H Tamaki… - Journal of muscle …, 2010 - Springer
We determine the effects of direct electrical stimulation (ES) on the histological profiles in
atrophied skeletal muscle fibers after denervation caused by nerve freezing. Direct ES was …

Electrical stimulation increases matrix metalloproteinase‐2 gene expression but does not change its activity in denervated rat muscle

TL Russo, SM Peviani, JLQ Durigan… - Muscle & Nerve …, 2008 - Wiley Online Library
Muscle‐fiber atrophy occurs concomitantly with intramuscular connective tissue proliferation
following denervation. These events contribute to the impairment of mechanical and …

Effect of electromyostimulation on apoptosis‐related factors in denervation and reinnervation of rat skeletal muscles

JY Lim, TR Han - Muscle & nerve, 2010 - Wiley Online Library
Electromyostimulation (EMS) has been utilized to reduce muscle atrophy, but its effect on
denervated muscles is controversial. This study was performed to determine the effect of …

Acute electrical stimulation modifies cross-sectional area and desmin protein in the skeletal muscle of old rats submitted to hindlimb suspension

G Marzuca-Nassr, R Droguett-Cervela… - 2017 - 200.9.234.120
The aim was to determine the acute effects of high-frequency electrical stimulation (HFES)
on the morphohistology and desmin content of the soleus, tibialis anterior (TA) and extensor …

Low-frequency electrical stimulation of bilateral hind legs by belt electrodes is effective for preventing denervation-induced atrophies in multiple skeletal muscle …

H Uno, S Kamiya, R Akimoto, K Hosoki, S Tadano… - Scientific Reports, 2022 - nature.com
Belt electrode skeletal muscle electrical stimulation (B-SES) can simultaneously contract
multiple muscle groups. Although the beneficial effects of B-SES in clinical situations have …

Electrical stimulation based on chronaxie increases fibrosis and modulates TWEAK/Fn14, TGF-β/myostatin, and MMP pathways in denervated muscles

CM Pinheiro-Dardis, TL Russo - American Journal of Physical …, 2017 - journals.lww.com
Objective The aim of this work was to investigate the effects of electrical stimulation (ES) of
denervated muscles of rat in neuromuscular performance, muscle atrophy, and fibrosis …

[PDF][PDF] Electrical stimulation of denervated rat skeletal muscle retards trabecular bone loss in early stages of disuse musculoskeletal atrophy

H Tamaki, K Tomori, K Yotani, F Ogita… - J Musculoskelet …, 2014 - ismni.org
Objectives: We aimed to determine the intensity of muscle stimulation required to prevent
structural failure as well as bone and skeletal muscle loss after denervation-induced disuse …