Evaluation of the atrial natriuretic peptide gene in stroke

N Kato, K Ikeda, T Nabika, H Morita, T Sugiyama… - Atherosclerosis, 2002 - Elsevier
The atrial natriuretic peptide (ANP) gene was, though inconclusive, implied to be
etiologically related to stroke in rats and recently in humans. The present study tested the …

The gene encoding atrial natriuretic peptide and the risk of human stroke

S Rubattu, P Ridker, MJ Stampfer, M Volpe… - Circulation, 1999 - Am Heart Assoc
Background—Recent evidence from an animal model of stroke, the stroke-prone
spontaneously hypertensive rat, implicated the gene encoding atrial natriuretic peptide …

Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease

A Hassan, N Ali, Y Dong, ND Carter, HS Markus - Neurology, 2001 - AAN Enterprises
The atrial natriuretic peptide (ANP) gene may underlie stroke susceptibility and sensitivity to
cerebral ischemia in an animal model of stroke. The authors investigate its role in humans …

Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans

S Rubattu, R Stanzione, E Di Angelantonio, B Zanda… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—A precise definition of genetic factors responsible for common
forms of stroke is still lacking. The purpose of the present study was to investigate the …

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites

NL Pereira, N Tosakulwong, CG Scott… - Circulation …, 2015 - Am Heart Assoc
Background—The goal of this study was to identify genetic determinants of plasma N-
terminal proatrial natriuretic peptide (NT-proANP) in the general community by performing a …

Role of a molecular variant of rat atrial natriuretic peptide gene in vascular remodeling

P De Paolis, V Nobili, A Lombardi… - Annals of Clinical & …, 2007 - Assoc Clin Scientists
Previous studies in a hypertensive animal model of stroke and in humans showed that
mutations of the atrial natriuretic peptide (ANP) gene are associated with increased risk of …

Association study between the variants of the human ANP gene and essential hypertension

D Rahmutula, T Nakayama, M Soma… - Hypertension …, 2001 - jstage.jst.go.jp
抄録 Variants of atrial natriuretic peptide (ANP) are reported to be more common in blacks
with hypertension than in normotensive controls and constitute an independent risk factor for …

Genetic analysis of the atrial natriuretic peptide gene in essential hypertension

N KATO, T SUGIYAMA, H MORITA, T NABIKA… - Clinical …, 2000 - portlandpress.com
Atrial natriuretic peptide (ANP) plays an important role in the regulation of blood pressure
through sodium–water homoeostasis. Accordingly, several investigators have raised the …

Study of genotype frequencies of ANP 664G/A polymorphism in normal subjects and CVD patients, and its association with plasma ANP levels

A Ohta, A Sonoda, Y Yatabe, E Takeshita… - Rinsho byori. The …, 2002 - europepmc.org
Atrial natriuretic peptide (ANP) plays a crucial role in regulating body fluid volume and blood
pressure, by promoting natriuresis and vasodilatation and by inhibiting the renin-angiotensin …

Differential brain atrial natriuretic peptide expression co-segregates with occurrence of early stroke in the stroke-prone phenotype of the spontaneously hypertensive …

S Rubattu, R Giliberti, U Ganten… - Journal of hypertension, 1999 - journals.lww.com
Objective To determine how the downregulation of atrial natriuretic peptide (ANP) gene
expression, previously demonstrated to occur only in the brain of the stroke-prone …