Rapid access to amino-substituted quinoline,(di) benzofuran, and carbazole heterocycles through an aminobenzannulation reaction

M Tiano, P Belmont - The Journal of Organic Chemistry, 2008 - ACS Publications
The use of a powerful aminobenzannulation reaction has been applied for the synthesis of
amino-substituted quinolines, dibenzofurans, and carbazoles. The precursors are …

Synthesis of highly substituted quinolines via a tandem ynamide benzannulation/iodocyclization strategy

TP Willumstad, PD Boudreau… - The Journal of Organic …, 2015 - ACS Publications
A two-stage “tandem strategy” for the regiocontrolled synthesis of very highly substituted
quinolines is described. Benzannulation based on the reaction of cyclobutenones or diazo …

Copper-catalyzed heteroannulation: a simple route to the synthesis of pyrrolo [2, 3-b] carbazole and pyrrolo [2, 3-b] quinoline derivatives

KS Prakash, R Nagarajan - Tetrahedron Letters, 2015 - Elsevier
A simple and efficient method for the synthesis of biologically important pyrrolo [2, 3-b]
carbazoles and pyrrolo [2, 3-b] quinolines is described. This involves the reaction of …

Diels–Alder and Michael addition reactions of indoles with masked o-benzoquinones: synthesis of highly functionalized hydrocarbazoles and 3-arylindoles

MF Hsieh, PD Rao, CC Liao - Chemical Communications, 1999 - pubs.rsc.org
Diels–Alder and Michael addition reactions of indoles with masked o-benzoquinones:
synthesis of highly functionalized hydrocar Page 1 OH OMe R DAIB O OMe OMe R HN H H O …

Redox-annulation of cyclic amines and β-ketoaldehydes

W Chen, D Seidel - Organic letters, 2016 - ACS Publications
Benzo [a] quinolizine-2-one derivatives are readily assembled from 1, 2, 3, 4-
tetrahydroisoquinoline and β-ketoaldehydes by means of a new intramolecular redox …

Heterocyclic synthesis via a tandem aza-Wittig reaction/heterocumulene-mediated annulation reaction. New methodology for the preparation of quinazoline …

P Molina, M Alajarín, A Vidal - Tetrahedron letters, 1988 - Elsevier
The aza-Wittig reaction of iminophosphoranes derived fromN-substituted o-
azidobenzamides or 2-(o-azido) phenyl benzimidazolewith isocyanates, carbon dioxide or …

Synthesis of quinolines through three-component cascade annulation of aryl diazonium salts, nitriles, and alkynes

H Wang, Q Xu, S Shen, S Yu - The Journal of Organic Chemistry, 2017 - ACS Publications
An efficient and rapid synthesis of multiply substituted quinolines is described. This method
is enabled by a three-component cascade annulation of readily available aryl diazonium …

Steric and electronic limitations for the Dötz benzannulation of aromatic alkynes

JC Anderson, JW Cran, NP King - Tetrahedron letters, 2002 - Elsevier
As part of an investigation into a new strategy for biaryl synthesis, the Dötz benzannulation
of a series of substituted aryl acetylenes was undertaken to determine possible steric and …

The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles

JE Baldwin, GJ Pritchard, RE Rathmell - Journal of the Chemical …, 2001 - pubs.rsc.org
The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl
substituted pyrimidines and pyrazoles - Journal of the Chemical Society, Perkin Transactions 1 …

Metal-free transannulation reaction of indoles with nitrostyrenes: A simple practical synthesis of 3-substituted 2-quinolones

AV Aksenov, AN Smirnov, NA Aksenov… - Chemical …, 2013 - pubs.rsc.org
3-Substituted 2-quinolones are obtained via a novel, metal-free transannulation reaction of 2-
substituted indoles with 2-nitroalkenes in polyphosphoric acid. The reaction can be used in …