Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair

CP Lu, L Polak, AS Rocha, HA Pasolli, SC Chen… - Cell, 2012 - cell.com
Sweat glands are abundant in the body and essential for thermoregulation. Like mammary
glands, they originate from epidermal progenitors. However, they display few signs of …

Sweat gland progenitors in development, homeostasis, and wound repair

C Lu, E Fuchs - Cold Spring Harbor perspectives …, 2014 - perspectivesinmedicine.cshlp.org
The human body is covered with several million sweat glands. These tiny coiled tubular skin
appendages produce the sweat that is our primary source of cooling and hydration of the …

Lineage analysis of epidermal stem cells

MP Alcolea, PH Jones - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Lineage tracing involves labeling cells to track their subsequent behavior within the normal
tissue environment. The advent of genetic lineage tracing and cell proliferation assays …

Sweat gland organoids contribute to cutaneous wound healing and sweat gland regeneration

J Diao, J Liu, S Wang, M Chang, X Wang, B Guo… - Cell Death & …, 2019 - nature.com
Sweat glands perform a vital thermoregulatory function in mammals. Like other skin
components, they originate from epidermal progenitors. However, they have low …

Epithelial skin biology: three decades of developmental biology, a hundred questions answered and a thousand new ones to address

E Fuchs - Current topics in developmental biology, 2016 - Elsevier
The mammalian skin epidermis and its hair and sweat gland appendages provide a
protective barrier that retains essential body fluids, guards against invasion by harmful …

More than one way to skin...

E Fuchs, V Horsley - Genes & development, 2008 - genesdev.cshlp.org
Epithelial stem cells in the skin are specified during development and are governed by
epithelial–mesenchymal interactions to differentially adopt the cell fates that enable them to …

Identification of stem cells in the secretory complex of salivary glands

M Kwak, N Alston… - Journal of dental research, 2016 - journals.sagepub.com
Salivary glands have an essential secretory function for maintaining oral and overall health.
The epithelial compartment of the gland is composed of several highly specialized cell types …

Regeneration of functional sweat gland‐like structures by transplanted differentiated bone marrow mesenchymal stem cells

Z Sheng, X Fu, S Cai, Y Lei, T Sun… - Wound Repair and …, 2009 - Wiley Online Library
Regeneration of sweat glands after deep burns has been an unsolved problem. Owing to
lack of perspiration, survivors of an extensive deep burn injury are leading a miserable life in …

Epithelial stem cells and implications for wound repair

MV Plikus, DL Gay, E Treffeisen, A Wang… - Seminars in cell & …, 2012 - Elsevier
Activation of epithelial stem cells and efficient recruitment of their proliferating progeny plays
a critical role in cutaneous wound healing. The reepithelialized wound epidermis has a …

Markers of epidermal stem cell subpopulations in adult mammalian skin

K Kretzschmar, FM Watt - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
The epidermis is the outermost layer of mammalian skin and comprises a multilayered
epithelium, the interfollicular epidermis, with associated hair follicles, sebaceous glands …