Aerobic bioreactors are widely used in the synthesis of value-added products in
pharmaceutical and biotechnology industries, wherein microbial bioreactions aid in the …

Aerobic/anaerobic and gas fermentation pathways have emerged as promising new
technologies for the generation of renewable fuels/chemicals from biomass derived sugars …

Hydrodynamics, oxygen transfer, and oxygen uptake in bubble-column and airlift bioreactors
were studied using multiphase Euler-Euler computational fluid dynamics (CFD) simulations …

Mechanically-agitated reactors are widely used in aerobic fermentation, because they
provide good mixing of reactants and high performance in terms of oxygen mass transfer. In …

Spatial variation of microorganism populations in stirred-tank bioreactors, caused by the
interactions of complex multiphase flows and microorganism metabolism, results in …

Industrially relevant bioprocesses such as paraffin activation present a complex multiphase
system consisting of an aqueous growth medium and an immiscible alkane phase that is …

The microbe, Zymomonas mobilis, can efficiently convert sugars to 2, 3 butanediol (BDO), an
important intermediate for downstream chemical products, only in a well-controlled …

In many biological processes, increasing the rate of transport of a limiting nutrient can
enhance the rate of product formation. In aerobic fermentation systems, the rate of oxygen …

The Covid-19 pandemic highlighted the importance of quickly scaling up the production of
vaccines and other pharmaceutical products. These products are typically made within …

Abstract The application of Computational Fluid Dynamics to aerobic fermentations faces
several issues, such as validation of multiphase models at high gas holdup and with …