Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …

Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

BACKGROUND Metabolic reprogramming is a hallmark of malignancy first recognized a
century ago. In some cases, reprogrammed metabolic activities can be exploited to …

Tumors reprogram pathways of nutrient acquisition and metabolism to meet the
bioenergetic, biosynthetic, and redox demands of malignant cells. These reprogrammed …

As an important component of the tumor microenvironment, cancer-associated fibroblasts
(CAFs) secrete energy metabolites to supply energy for tumor progression. Abnormal …

Tumor metabolism is reorganized to support proliferation in the face of growth-related stress.
Unlike the widespread profiling of changes to metabolic enzyme levels in cancer …

Abstract Background and Aims: Cancer cells prefer aerobic glycolysis to maintain growth
advantages, but the role of long non-coding RNAs (lncRNAs) in glycometabolism still …

Metabolic reprogramming contributes to tumor development and introduces metabolic
liabilities that can be exploited to treat cancer. Chemotherapies targeting metabolism have …

Cancer is a complex disease of multiple alterations occuring at the epigenomic, genomic,
transcriptomic, proteomic and/or metabolic levels. The contribution of genetic mutations in …

Non-covalent complexes of glycolytic enzymes, called metabolons, were postulated in the
1970s, but the concept has been controversial. Here we show that a c-Myc-responsive long …