Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions

R Noroozi, W Branicki, K Pyrc, PP Łabaj, E Pospiech… - Cytokine, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic in early 2020. The infection has been associated with a wide range of clinical …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
Clinical intervention in patients with corona virus disease 2019 (COVID-19) has
demonstrated a strong upregulation of cytokine production in patients who are critically ill …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
Objective A critical role in coronavirus disease 2019 (COVID-19) pathogenesis is played by
immune dysregulation that leads to a generalized uncontrolled multisystem inflammatory …

Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …