Overexpression of alpha-synuclein and oxidative stress has been implicated in the neuronal
cell death in Parkinson's disease. Alpha-synuclein associates with mitochondria and …

Recently, it has been shown that rotenone, a specific inhibitor of mitochondrial complex I, is
a useful tool in animal models of Parkinson's disease, but the mechanism of rotenone …

1-Methyl-4-phenylpyridinium (MPP+) is a neurotoxin that causes Parkinson's disease in
experimental animals and humans. Despite the fact that intracellular iron was shown to be …

Cypermethrin induces the mitochondrial dysfunction and oxidative damage to the
nigrostriatal dopaminergic neurons leading to Parkinsonism in rats. Despite α-synuclein …

Oxidative stress has been implicated in the etiology of Parkinson's disease (PD). The
important biochemical features of PD, being profound deficit in dopamine (DA) content …

α-Synuclein is a key component of Lewy bodies in the brain of patients with Parkinson's
disease (PD) and recent studies suggest that oxidative stress reactions might contribute to …

This study has shown that purified recombinant human α‐synuclein (20 μM) causes
membrane depolarization and loss of phosphorylation capacity of isolated purified rat brain …

Glioblastoma is the most malignant and prevalent brain tumor that still remains incurable.
Recent studies reported anti-cancer effect of the broccoli-derived compound sulforaphane …

Abstract Parkinson's disease (PD), the second most common neurodegenerative disease,
impairs motor skills and cognitive function. To date, the drugs used for PD treatment provide …

α-Synuclein is a neuron-specific protein that contributes to the pathology of Parkinson's
disease via mitochondria-related mechanisms. The present study investigated possible …