Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review

K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background On the 11 March 2020, the World Health Organization (WHO) declared that
COVID-19 was a pandemic. To date, there are no medical treatments for COVID-19 with …

[HTML][HTML] Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …

[HTML][HTML] Hydroxychloroquine is effective, and consistently so when provided early, for COVID-19: a systematic review

C Prodromos, T Rumschlag - New microbes and new infections, 2020 - Elsevier
Hydroxychloroquine (HCQ) has shown efficacy against coronavirus disease 2019 (COVID-
19) in some but not all studies. We hypothesized that a systematic review would show HCQ …

A rapid systematic review of clinical trials utilizing chloroquine and hydroxychloroquine as a treatment for COVID‐19

MDS Chowdhury, J Rathod… - Academic Emergency …, 2020 - Wiley Online Library
Objectives The emergence of SARS‐CoV‐2 has presented clinicians with a difficult
therapeutic dilemma. With supportive care as the current mainstay of treatment, the fatality …

[HTML][HTML] An updated systematic review of the therapeutic role of hydroxychloroquine in coronavirus disease-19 (COVID-19)

S Das, S Bhowmick, S Tiwari, S Sen - Clinical drug investigation, 2020 - Springer
Abstract Background and Objective The world is currently experiencing the Coronavirus
Disease-19 (COVID-19) pandemic. There is no approved drug for the definitive treatment of …

Update on use of chloroquine/hydroxychloroquine to treat coronavirus disease 2019 (COVID-19)

J Gao, S Hu - Bioscience trends, 2020 - jstage.jst.go.jp
Drugs that are specifically efficacious against SARS-CoV-2 have yet to be established.
Chloroquine and hydroxychloroquine have garnered considerable attention for their …

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

A Cortegiani, G Ingoglia, M Ippolito, A Giarratano… - Journal of critical …, 2020 - Elsevier
Abstract Purpose COVID-19 (coronavirus disease 2019) is a public health emergency of
international concern. As of this time, there is no known effective pharmaceutical treatment …

Chloroquine and hydroxychloroquine for the prevention and treatment of COVID-19: A fiction, hope or hype? An updated review

SAM Saghir, NA AlGabri, MM Alagawany… - … and clinical risk …, 2021 - Taylor & Francis
In December 2019, the novel coronavirus disease pandemic (COVID-19) that began in
China had infected so far more than 109,217,366 million individuals worldwide and …

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial

Z Chen, J Hu, Z Zhang, S Jiang, S Han, D Yan… - medrxiv, 2020 - medrxiv.org
Aims Studies have indicated that chloroquine (CQ) shows antagonism against COVID-19 in
vitro. However, evidence regarding its effects in patients is limited. This study aims to …

Efficacy of chloroquine or hydroxychloroquine in COVID-19 patients: a systematic review and meta-analysis

Z Kashour, M Riaz, MA Garbati… - Journal of …, 2021 - academic.oup.com
Objectives Clinical studies of chloroquine (CQ) and hydroxychloroquine (HCQ) in COVID-19
disease reported conflicting results. We sought to systematically evaluate the effect of CQ …