Background: The incidence of depression is 0.9% in preschoolers, 1.9% in school age
children, and 4.7% in adolescents. Current antidepressant treatment of mood disorders in …

BACKGROUND:: This report presents results from the acute treatment phase of a clinical
trial designed to confirm efficacy of a fixed dose of 20 mg of fluoxetine in children and …

Introduction: Despite an increasing number of studies, there is debate whether
antidepressants have a favorable benefit/risk balance in depressed youth. Areas covered: A …

Background: Depression is a major cause of morbidity and mortality in children and
adolescents. To date, randomized, controlled, double-blind trials of antidepressants (largely …

Fifteen adolescents and young adults (ages 16–24) with a DSM-III-R diagnosis of major
depression, who failed to respond to prior treatment with tricyclic antidepressants, were …

Objective: Major depressive disorder is a severe disorder that has a significant impact on the
psychological and social functioning of children and adolescents. Considering current …

Background Depression is a common psychiatric disorder worldwide, including in Iran, and
is estimated to affect 10%–15% of the population. Antidepressant drugs can have multiple …

Objective: The aim of this study was to present the reliability and validity of the Children's
Depression Rating Scale–Revised (CDRS-R) in the adolescent age group. Method …

Background Fluoxetine is a serotonin-specific reuptake inhibitor antidepressant and is the
only approved pharmacological treatment for major depressive disorder (MDD) in children …

Antidepressant agents are widely prescribed for adolescents, although specific data
regarding their efficacy in this age range are limited. The aims of the present article are to …