Despite the tremendous progress in the clinical management of autoimmune diseases, many patients do not respond to the currently used treatments. Autoreactive B cells play a …
In the clinic, chimeric antigen receptor–modified T (CAR T) cell therapy is frequently associated with life-threatening cytokine-release syndrome (CRS) and neurotoxicity …
M Kawabori, AH Weintraub, H Imai, I Zinkevych… - Neurology, 2021 - AAN Enterprises
Objective To determine whether chronic motor deficits secondary to traumatic brain injury (TBI) can be improved by implantation of allogeneic modified bone marrow–derived …
J Zhang, Y Hu, J Yang, W Li, M Zhang, Q Wang… - Nature, 2022 - nature.com
Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating haematological malignancies,,,,,–. However, CAR-T cell therapy currently has …
F Del Bufalo, M Becilli, C Rosignoli… - Blood, The Journal …, 2023 - ashpublications.org
Autologous CD19-directed chimeric antigen receptor (CAR)-T cells have shown unprecedented efficacy in children with relapsed/refractory B-cell precursor acute …
E Dolgin - Nature Biotechnology, 2021 - go.gale.com
BTK blockers make headway in multiple sclerosis - Document - Gale Academic OneFile Use this link to get back to this page. Copy Skip to Content Library Menu: Google Scholar Discovery …
CJ Turtle, LA Hanafi, C Berger… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. T cells that have been modified to express a CD19-specific chimeric antigen receptor (CAR) have antitumor activity in B cell malignancies; however, identification …