Elixir for DCs | Nature Reviews Immunology Skip to main content Thank you for visiting
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Defective host defenses later in life are associated with changes in immune cell activities,
suggesting that age-specific considerations are needed in immunotherapy approaches. In …

Defective host defenses later in life are associated with changes in immune system activity.
The means to correct immune defects to ensure immunity in the elderly are undefined. In this …

The safety and feasibility of dendritic cell (DC)-based immunotherapies in cancer
management have been well documented after more than twenty-five years of …

Balancing life and death | Nature Immunology Skip to main content Thank you for visiting
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Immunosenescence poses a significant challenge to tumor immunotherapy in elderly
individuals. In this issue of Cell, Zhivaki et al. elucidate that dendritic cells “hyperactivated” …

Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system.
They serve as the sentinels that capture antigens in the periphery, process them into …

Effective cancer immunotherapy depends on the body's ability to generate tumor antigen-
presenting cells and tumor-reactive effector lymphocytes. As the most potent antigen …

Cancer vaccine strategies require the transfer of tumor-associated antigens from tumor cells
to antigenpresenting cells (APCs) for degradation and presentation of peptide fragments on …

While the term'magic bullet'has resulted in the association of cancer immunotherapy with the
use of monoclonal antibodies to target tumours, it is clear that the most effective way to …