Background Metagenomics seeks to understand microbial communities and assemblages
by DNA sequencing. Technological advances in next generation sequencing technologies …

The analysis of microbiota composition in humans, animals, and built environments is
important because of emerging roles and applications in a broad range of disease and …

Background New developments in next-generation sequencing technologies and massive
data received from this approach open wide prospects for personalised medicine and …

The gut microbiome is widely analyzed using high-throughput sequencing, such as 16S
rRNA gene amplicon sequencing and shotgun metagenomic sequencing (SMS). DNA …

The human microbiome has emerged as a major player in regulating human health and
disease. Translational studies of the microbiome have the potential to indicate clinical …

High-throughput molecular technologies can profile microbial communities at high
resolution even in complex environments like the intestinal microbiota. Recent …

Background Deep sequencing of the variable region of 16S rRNA genes has become the
predominant tool for studying microbial ecology. As sequencing datasets have accumulated …

Shotgun metagenomics enables the reconstruction of complex microbial communities at a
high level of detail. Such an approach can be conducted using both short-read and long …

Sequencing of the 16S rRNA gene (16S) has long been a go-to method for microbiome
characterization due to its accessibility and lower cost compared to shotgun metagenomic …

The study of microbial communities has undergone significant advancements, starting from
the initial use of 16S rRNA sequencing to the adoption of shotgun metagenomics. However …