Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19

C Herr, S Mang, B Mozafari, K Guenther… - Journal of …, 2021 - Taylor & Francis
Background COVID-19 comprises several severity stages ranging from oligosymptomatic
disease to multi-organ failure and fatal outcomes. The mechanisms why COVID-19 is a mild …

[HTML][HTML] Cytokine elevation in severe COVID-19 from longitudinal proteomics analysis: comparison with sepsis

T Ebihara, H Matsumoto, T Matsubara… - Frontiers in …, 2022 - frontiersin.org
Introduction Coronavirus disease 2019 (COVID-19) is a new viral disease. Uncontrolled
inflammation called “cytokine storm” is reported to contribute to disease pathogenesis as …

Unveiling COVID-19 secrets: Harnessing Cytokines as powerful biomarkers for diagnosis and predicting severity

B Wolszczak-Biedrzycka, J Dorf… - Journal of …, 2023 - Taylor & Francis
Introduction In coronavirus disease (COVID-19), inflammation takes center stage, with a
cascade of cytokines released, contributing to both inflammation and lung damage. The …

[HTML][HTML] A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

Biomarkers associated with COVID-19 disease progression

G Ponti, M Maccaferri, C Ruini, A Tomasi… - Critical reviews in …, 2020 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and
social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Serial measurement of cytokines strongly predict COVID-19 outcome

HS Ozger, R Karakus, EN Kuscu, UE Bagriacik… - PloS one, 2021 - journals.plos.org
Purpose Cytokines are major mediators of COVID-19 pathogenesis and several of them are
already being regarded as predictive markers for the clinical course and outcome of COVID …

[HTML][HTML] Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients

L Sanchez-de Prada, O Gorgojo-Galindo… - Frontiers in …, 2022 - frontiersin.org
Background High cytokine levels have been associated with severe COVID-19 disease.
Although many cytokine studies have been performed, not many of them include …

Biological responses to COVID-19: Insights from physiological and blood biomarker profiles

R Zakeri, A Pickles, E Carr, DM Bean… - Current research in …, 2021 - Elsevier
Background Understanding the spectrum and course of biological responses to coronavirus
disease 2019 (COVID-19) may have important therapeutic implications. We sought to …

Selection of an optimal combination panel to better triage COVID-19 hospitalized patients

Y Tang, Y Li, J Sun, H Pan, F Yao… - Journal of inflammation …, 2020 - Taylor & Francis
Purpose It is difficult to predict the prognosis of COVID-19 patients at the disease onset. This
study was designed to add new biomarkers into conventional inflammatory panels to build …

Laboratory biomarkers associated with COVID-19 severity and management

S Keddie, O Ziff, MKL Chou, RL Taylor, A Heslegrave… - Clinical …, 2020 - Elsevier
The heterogeneous disease course of COVID-19 is unpredictable, ranging from mild self-
limiting symptoms to cytokine storms, acute respiratory distress syndrome (ARDS), multi …