Roles of flavonoids against coronavirus infection

M Russo, S Moccia, C Spagnuolo, I Tedesco… - Chemico-biological …, 2020 - Elsevier
In terms of public health, the 21st century has been characterized by coronavirus
pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged …

In silico evaluation of natural flavonoids as a potential inhibitor of coronavirus disease

P Kashyap, M Thakur, N Singh, D Shikha, S Kumar… - Molecules, 2022 - mdpi.com
The recent coronavirus disease (COVID-19) outbreak in Wuhan, China, has led to millions of
infections and the death of approximately one million people. No targeted therapeutics are …

Commercially available flavonols are better SARS-CoV-2 inhibitors than isoflavone and flavones

OA Chaves, N Fintelman-Rodrigues, X Wang… - Viruses, 2022 - mdpi.com
Despite the fast development of vaccines, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still circulating and generating variants of concern (VoC) that escape the …

Naturally available flavonoid aglycones as potential antiviral drug candidates against SARS-CoV-2

AA Al-Karmalawy, MM Farid, A Mostafa, AY Ragheb… - Molecules, 2021 - mdpi.com
Flavonoids are important secondary plant metabolites that have been studied for a long time
for their therapeutic potential in inflammatory diseases because of their cytokine-modulatory …

Polyphenols as promising biologically active substances for preventing SARS-CoV-2: A review with research evidence and underlying mechanisms

T Mehany, I Khalifa, H Barakat, SA Althwab, YM Alharbi… - Food Bioscience, 2021 - Elsevier
Currently, antiviral drugs and/or vaccines are not yet available to treat or prevent severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this review, we narrated the …

Role of phytoconstituents in the management of COVID-19

A Das, D Pandita, GK Jain, P Agarwal… - Chemico-biological …, 2021 - Elsevier
Background COVID-19, a severe global pandemic caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has emerged as one of the most threatening …

[HTML][HTML] Computational and network pharmacology analysis of bioflavonoids as possible natural antiviral compounds in COVID-19

R Patil, R Chikhale, P Khanal, N Gurav… - Informatics in medicine …, 2021 - Elsevier
Bioflavonoids are the largest group of plant-derived polyphenolic compounds with diverse
biological potential and have also been proven efficacious in the treatment of Severe Acute …

A review of natural products, their effects on SARS-CoV-2 and their utility as lead compounds in the discovery of drugs for the treatment of COVID-19

RL Chapman, SV Andurkar - Medicinal Chemistry Research, 2022 - Springer
During the COVID-19 pandemic lasting now for well more than a year, nearly 247 million
cases have been diagnosed and over 5 million deaths have been recorded worldwide as of …

A role for quercetin in coronavirus disease 2019 (COVID‐19)

G Derosa, P Maffioli, A D'Angelo… - Phytotherapy …, 2021 - Wiley Online Library
Several months ago, an outbreak of pneumonia of unknown aetiology was detected in
Wuhan City (China) and the aetiological agent of the atypical pneumonia was isolated by …

Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2

W Liu, W Zheng, L Cheng, M Li, J Huang, S Bao… - Natural Products and …, 2022 - Springer
The most recent outbreak of 2019 novel coronavirus, named as COVID-19, caused
pneumonia epidemic in Wuhan with 2121 deaths cases as of February 20th 2020 …