A critical evaluation of risk to reward ratio of quercetin supplementation for COVID‐19 and associated comorbid conditions

A Pawar, M Russo, I Rani, K Goswami… - Phytotherapy …, 2022 - Wiley Online Library
The interim results of the large, multinational trials on coronavirus disease 2019 (COVID‐19)
using a combination of antiviral drugs appear to have little to no effect on the 28‐day …

Curcumin as a potential treatment for COVID-19

BAC Rattis, SG Ramos, MRN Celes - Frontiers in pharmacology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease that rapidly spread
throughout the world leading to high mortality rates. Despite the knowledge of previous …

Natural products for COVID‐19 prevention and treatment regarding to previous coronavirus infections and novel studies

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2021 - Wiley Online Library
Recently, the novel life‐threatening coronavirus infection (COVID‐19) was reported at the
end of 2019 in Wuhan, China, and spread throughout the world in little time. The effective …

[HTML][HTML] SARS-CoV-2 neutralizing activity of polyphenols in a special green tea extract preparation

E Kicker, G Tittel, T Schaller, EM Pferschy-Wenzig… - Phytomedicine, 2022 - Elsevier
Background The COVID-19 pandemic will continue to threaten our health care systems in
the next years. In addition to vaccination there is a need for effective tools for prevention and …

Flavonoids activation of the transcription factor Nrf2 as a hypothesis approach for the prevention and modulation of SARS-CoV-2 infection severity

P Mendonca, KFA Soliman - Antioxidants, 2020 - mdpi.com
The Nrf2-Keap1-ARE pathway is the principal regulator of antioxidant and phase II
detoxification genes. Its activation increases the expression of antioxidant and cytoprotective …

[HTML][HTML] Shufeng Jiedu, a promising herbal therapy for moderate COVID-19: Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a …

XIA Lu, SHI Yujing, SU Jie, T Friedemann… - Phytomedicine, 2021 - Elsevier
Abstract Background Shufeng Jiedu capsules (SFJDC), a patented herbal drug composed of
eight medicinal plants, is used for the treatment of different viral respiratory tract infectious …

Quercetin and vitamin C: an experimental, synergistic therapy for the prevention and treatment of SARS-CoV-2 related disease (COVID-19)

RML Colunga Biancatelli, M Berrill… - Frontiers in …, 2020 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) represents an emergent
global threat which is straining worldwide healthcare capacity. As of May 27th, the disease …

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

J Gasparello, E D'Aversa, C Papi, L Gambari, B Grigolo… - Phytomedicine, 2021 - Elsevier
Background A key clinical feature of COVID-19 is a deep inflammatory state known as
“cytokine storm” and characterized by high expression of several cytokines, chemokines and …

Cytokine storm in COVID‐19 and parthenolide: Preclinical evidence

M Bahrami, M Kamalinejad, SA Latifi… - Phytotherapy …, 2020 - Wiley Online Library
A group of patients with pneumonia caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) were reported from China in December 2019. Although …