COVID‐19: A case for inhibiting NLRP3 inflammasome, suppression of inflammation with Curcumin?

A Saeedi‐Boroujeni… - Basic & Clinical …, 2021 - Wiley Online Library
Curcumin is the effective ingredient of turmeric, sometimes used as a painkiller in traditional
medicine. It has extensive biological properties such as anti‐inflammatory and antioxidant …

Pharmacological (or synthetic) and nutritional agonists of PPAR-γ as candidates for cytokine storm modulation in COVID-19 disease

C Ciavarella, I Motta, S Valente, G Pasquinelli - Molecules, 2020 - mdpi.com
The cytokine storm is an abnormal production of inflammatory cytokines, due to the over-
activation of the innate immune response. This mechanism has been recognized as a critical …

COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …

Macrophage responses associated with COVID-19: A pharmacological perspective

GW Booz, R Altara, AH Eid, Z Wehbe, S Fares… - European Journal of …, 2020 - Elsevier
COVID-19 has caused worldwide death and economic destruction. The pandemic is the
result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has …

A triple‐blind, placebo‐controlled, randomized clinical trial to evaluate the effect of curcumin‐containing nanomicelles on cellular immune responses subtypes and …

M Hassaniazad, E Eftekhar… - Phytotherapy …, 2021 - Wiley Online Library
In COVID‐19 patients, cytokine storm due to excessive immune responses can cause
severe complications. In this study, we investigated the effect of curcumin nanomicelles on …

The role and therapeutic potential of NF-kappa-B pathway in severe COVID-19 patients

A Hariharan, AR Hakeem, S Radhakrishnan… - …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) pandemic has affected health care systems
worldwide. Severe presentations of COVID-19 such as severe pneumonia and acute …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Novel CYP11A1-derived vitamin D and lumisterol biometabolites for the management of COVID-19

S Qayyum, RM Slominski, C Raman, AT Slominski - Nutrients, 2022 - mdpi.com
Vitamin D deficiency is associated with a higher risk of SARS-CoV-2 infection and poor
outcomes of the COVID-19 disease. However, a satisfactory mechanism explaining the …

Cascade of immune mechanism and consequences of inflammatory disorders

KB Megha, X Joseph, V Akhil, PV Mohanan - Phytomedicine, 2021 - Elsevier
Inflammatory responses arise as an outcome of tissues or organs exposure towards harmful
stimuli like injury, toxic chemicals or pathogenic microorganism. It is a complex cascade of …

Role of vitamins and minerals as immunity boosters in COVID-19

P Kumar, M Kumar, O Bedi, M Gupta, S Kumar… - …, 2021 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus
disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it …