Murine dendritic cells (DCs) can be classified into at least 2 subsets,“myeloid-
related”(CD11bbright, CD8α−) and “lymphoid-related”(CD11bdull, CD8α+), but the absolute …

We established a humanized mouse model incorporating FLT3-ligand (FLT3-L)
administration after hematopoietic cell reconstitution to investigate expansion, phenotype …

Using a recently described serum-free culture system of purified human CD34+ progenitor
cells, we show here a critical cooperation of flt3 ligand (FL) with transforming growth factor …

Dendritic cells (DCs) represent a family of ontogenically distinct leukocytes involved in
immune response regulation. The ability of DCs to stimulate T-cell immunity has led to their …

Dendritic cells (DC) are the most efficient APC for T cells. The clinical use of DC as vectors
for anti-tumor and infectious disease immunotherapy has been limited by their trace levels …

To gain ample numbers of dendritic cells (DCs) for investigation, or for immunotherapy, the
culture of DC precursors from bone marrow in either GM-CSF and IL-4 (GM/IL4-DCs) or …

Flt3 ligand (Flt3L) is a growth factor for hemopoietic progenitors and can promote the
expansion of both conventional dendritic cells (DCs) and plasmacytoid predendritic cells (p …

Stimulation of Flt3 receptor tyrosine kinase through its cognate ligand expands early
hematopoietic progenitor and dendritic cells (DCs) in humans and mice. The exact …

Bone marrow (BM)–derived dendritic cells (DCs) cultured in granulocyte-macrophage
colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4) have been used to generate …

Multiple subsets of FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent dendritic cells
(DCs) control T-cell tolerance and immunity. In mice, Batf3-dependent CD103+ DCs …