Mesenchymal stem cells empowering tendon regenerative therapies

R Costa-Almeida, I Calejo, ME Gomes - International journal of molecular …, 2019 - mdpi.com
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Mesenchymal stem cells in tendon repair and regeneration: basic understanding and translational challenges

DJ Leong, HB Sun - Annals of the New York Academy of …, 2016 - Wiley Online Library
Tendon injuries are common and present a clinical challenge because they often respond
poorly to treatment and require prolonged rehabilitation. Current treatments often do not …

Stem cell technology for tendon regeneration: current status, challenges, and future research directions

PPY Lui - Stem cells and cloning: advances and applications, 2015 - Taylor & Francis
Tendon injuries are a common cause of physical disability. They present a clinical challenge
to orthopedic surgeons because injured tendons respond poorly to current treatments …

Tendon regeneration and repair with adipose derived stem cells

A Cagri Uysal, H Mizuno - Current stem cell research & therapy, 2010 - ingentaconnect.com
Tendon, the crucial element of the musculoskeletal system, when damaged, never restores
the biological and biomechanical properties completely. Recently, tissue engineering and …

Stepwise differentiation of mesenchymal stem cells augments tendon-like tissue formation and defect repair in vivo

Z Yin, J Guo, T Wu, X Chen, L Xu, S Lin… - Stem cells …, 2016 - academic.oup.com
Tendon injuries are common and present a clinical challenge, as they often respond poorly
to treatment and result in long-term functional impairment. Inferior tendon healing responses …

Stem cells for tendon tissue engineering and regeneration

Z Yin, X Chen, J Chen, HW Ouyang - Expert opinion on biological …, 2010 - Taylor & Francis
Importance of the field: Tendon injuries are common especially in sports activities, but
tendon is a unique connective tissue with poor self-repair capability. With advances in stem …

Progress with stem cell therapies for tendon tissue regeneration

F Migliorini, M Tingart, N Maffulli - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction Chronic musculoskeletal pain is very prevalent, and accounts for major health-
care expenses. Many of the present therapeutic modalities are only partially effective, and …

Tendon repair through stem cell intervention: cellular and molecular approaches

R Bullough, T Finnigan, A Kay, N Maffulli… - Disability and …, 2008 - Taylor & Francis
Tendon injuries are common in either the workplace or sport activities, with some 3 to 5
million tendon and ligament injuries occurring annually worldwide. Management of tendon …

Tendon injuries: Basic science and new repair proposals

F Wu, M Nerlich, D Docheva - EFORT open reviews, 2017 - eor.bioscientifica.com
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons
become more prone to degeneration followed by injuries. Tendon repair often requires …

Tendon-derived stem cells (TDSCs): from basic science to potential roles in tendon pathology and tissue engineering applications

PPY Lui, KM Chan - Stem cell reviews and reports, 2011 - Springer
Traditionally, tendons are considered to only contain tenocytes that are responsible for the
maintenance, repair and remodeling of tendons. Stem cells, which are termed tendon …