Leading biologists and clinicians interested in aging convened to discuss biomarkers of
aging. The goals were to come to a consensus, construct an agenda for future research, and …

The concept of biomarkers of aging and age-related disease dates to the early 1980s as
scientists engaged in aging research worked to clearly define aging and separate processes …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

An increase in the number of older people experiencing disability and dependence is a
critical aspect of the demographic change that will emerge within Europe due to the rise in …

Human ageing is an extremely personal process leading across the life course of individuals
to large population heterogeneity in the decline of functional capacity, health and lifespan …

Background Higher numbers of senescent cells have been implicated in age-related
disease pathologies. However, whether different diseases have different senescent …

Many candidate biomarkers of human ageing have been proposed in the scientific literature
but in all cases their variability in cross-sectional studies is considerable, and therefore no …

In laboratory studies, potential geroprotective interventions have been created: more than
400 geroprotectors, several gene and cell therapies. Their translation into medical practice …

The identification of specific biomarkers of aging would be an important milestone in
gerontologic research. In this communication, the goals of identifying biomarkers of aging …

Frailty is a functional term that describes a decline in physiological functions that leads to
dependency, vulnerability to stressors, high risk for adverse health outcomes, increased risk …