Background: Spiro [4.5] decenones are privileged structural motifs occurring in various
biologically active natural and unnatural compounds. Moreover, they are very important …

Till date, the ipso-cyclization of propiolamides is limited to provide azaspiro [4, 5]
decatrienones. Herein, we present the first example of ipso-carbocyclization, leading to …

ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic
compounds having a quaternary carbon center. Furthermore, these compounds also serve …

A one-pot cascade process of benzyl enoldiazoacatates, initiated by dirhodium (II)-catalyzed
intramolecular cyclopropene formation, occurs via a subsequent Buchner reaction and Cope …

The development of green and sustainable approaches for the synthesis of small molecules
is always in demand. Oxetanes and azetidines are strained heterocycles that possess …

A highly selective cascade reaction that allows the direct transformation of dienallenes to
spirocyclobutenes (spiro [3.4] octenes) as single diastereoisomers has been developed. The …

A metal-and oxidant-free route for affording azaspiro [4.5] deca-6, 9-diene-3, 8-dione via
photomediated iodinated spirocyclization of N-(4-methoxybenzyl) propiolamide has been …

In this work, a selective synthetic strategy towards 1-azaspiro [4.5] deca-3, 6, 9-trien-8-ones
from N-tosyl-N-(prop-2-yn-1-yl) aniline is developed. The transformation proceeds smoothly …

A new, general method for the synthesis of spiro [4, 5] trienones is described by the
intramolecular ipso-halocyclization of 4-(p-unsubstituted-aryl)-1-alkynes. In the presence of …

A new C-center radical-triggered bicyclization cascade of N-tethered 1, 7-enynes for forming
28 examples of biologically interesting spirocyclohexadienone-containing cyclopenta [c] …