The pathogenesis of IgA nephropathy: what is new and how does it change therapeutic approaches?

J Floege - American journal of kidney diseases, 2011 - Elsevier
Immunoglobulin A (IgA) nephropathy is the most common glomerulonephritis worldwide. For
example, in Japan, full-blown IgA nephropathy has been detected in∼ 1.5% of all allograft …

[HTML][HTML] An update on the pathogenesis and treatment of IgA nephropathy

JK Boyd, CK Cheung, K Molyneux, J Feehally… - Kidney international, 2012 - Elsevier
Over the past two decades significant progress has been made in unravelling the complex
pathogenesis of immunoglobulin A nephropathy (IgAN). Excess amounts of poorly …

Insights into the role of mucosal immunity in IgA nephropathy

Y Zhang, H Zhang - Clinical Journal of the American Society of …, 2018 - journals.lww.com
IgA nephropathy is the most common form of primary GN worldwide. It is characterized by
the deposition of IgA1 (in particular, galactose-deficient IgA1) in the mesangial area of the …

Pathogenesis of IgA nephropathy: current understanding and implications for development of disease-specific treatment

B Knoppova, C Reily, RG King, BA Julian… - Journal of Clinical …, 2021 - mdpi.com
IgA nephropathy, initially described in 1968 as a kidney disease with glomerular
“intercapillary deposits of IgA-IgG”, has no disease-specific treatment and is a common …

Immune abnormalities in IgA nephropathy

M Gentile, L Sanchez-Russo, LV Riella… - Clinical Kidney …, 2023 - academic.oup.com
ABSTRACT Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide and it is characterized by mesangial IgA deposition …

Glomerular diseases: emerging tests and therapies for IgA nephropathy

PA Canetta, K Kiryluk, GB Appel - Clinical Journal of the American …, 2014 - journals.lww.com
The last decade has seen major progress in understanding the pathogenesis as well as the
prognosis and treatment of patients with IgA nephropathy (IgAN). Although the diagnostic …

Primary IgA nephropathy: current challenges and future prospects

RS Penfold, M Prendecki, S McAdoo… - International journal of …, 2018 - Taylor & Francis
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide,
exhibiting a variable clinical and pathological course and significantly contributing to the …

Idiopathic IgA nephropathy: pathogenesis, histopathology, and therapeutic options

JA Tumlin, MP Madaio, R Hennigar - Clinical Journal of the …, 2007 - journals.lww.com
IgA nephropathy is one of the most common causes of glomerulonephritis in the world.
Proliferative and crescentic forms of IgA are found in up to 30% of cases and are associated …

Primary IgA nephropathy: new insights into pathogenesis

J Barratt, J Feehally - Seminars in Nephrology, 2011 - Elsevier
Since its first description more than 40 years ago, IgA nephropathy has become the most
common pattern of primary glomerulonephritis identified in all areas of the world where renal …

Progress in the pathogenesis of IgA nephropathy.

BA Julian, M Tomana, J Novak… - Advances in Nephrology …, 1999 - europepmc.org
Despite 31 years of clinical and laboratory investigation, the pathogenesis of IgAN remains
largely enigmatic. However, it seems clear that IgA1 accumulates in the glomerular …