Cardiovascular disease (CVD) is the leading cause of death worldwide. Accumulating
evidence indicates that conventional cardiovascular risk factors are less precise predictors …

Increasing evidence shows that conventional cardiovascular risk factors are incompletely
predictive of cardiovascular disease, particularly in elderly individuals, suggesting that there …

A considerable volume of research over the last decade has focused on understanding the
fundamental mechanisms for the progression of atherosclerosis—the underlying cause for …

Cardiovascular disease (CVD) is a recognized age-dependent condition whose incidence is
set to increase due to the gradual aging of the population. Moreover, ischemic …

Abstract Purpose of Review Clonal hematopoiesis (CH) is a prevalent condition that results
from the acquisition of somatic mutations in hematopoietic stem cells. When these mutations …

Ageing and inflammation strongly drive the risk of cardiovascular disease. Work over the
past decade has uncovered a common condition characterized by the positive selection of …

Advancing age is the most powerful predictor of cardiovascular morbidity, mortality, and
disability. Age has traditionally been ignored as a risk factor for cardiovascular disease …

Aging is the predominant risk factor for atherosclerosis, the leading cause of death. Rare
smooth muscle cells (SMCs) clonally expand giving rise to up to~ 70% of atherosclerotic …

Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers,
and health systems. Structural and functional alterations of vessels accumulate throughout …

Traditional risk factors are incompletely predictive of cardiovascular disease development, a
leading cause of death in the elderly. Recent epidemiological studies have shown that …