At one level, obesity is clearly a problem of simple physics, a result of eating too much and
not expending enough energy. The more complex question, however, is why do some …

The current obesity epidemic is a consequence of a positive “energy gap” arising from an
imbalance between energy intake and expenditure. Complex genetic, environmental …

Obesity is a highly heritable multifactorial disease that places an enormous burden on
human health. Its increasing prevalence and the concomitant‐reduced life expectancy has …

Obesity is a heterogeneous disorder, its biological causes being complex. The escalating
frequency of obesity during the past few decades is due to environmental factors such as …

Abstract Purpose of Review Our review provides a brief summary of the most recent
advances towards the identification of the genetic basis of specific aspects of obesity and the …

The current global obesity epidemic has developed only over the past three decades and
cannot be explained by changes in our genome. It is more likely due to a changing …

The idea that a common set of genes with pleiotropic (multiple diverse) effects might
influence obesity, type 2 diabetes, and related traits such as sensitivity to the effects of …

Aim The obesity epidemic has been largely attributed to changes in lifestyle habits
established over the past three decades. These changes are mainly attributed to excessive …

The main enemy for the geneticist may not be the complexity, but the heterogeneity of
common diseases like obesity or Type 2 diabetes (T2D). The pragmatic approach of this …

Obesity and diabetes are common and complex metabolic diseases, with an increasing
prevalence worldwide that results from the interplay of genetic and environmental factors …