The obesity epidemic demands more insight into genetic predisposition, mechanisms,
prevention and therapeutic interventions. Opinions about how to prioritize obesity research …

An evolutionary approach to obesity involves a genomic/anthropological dimension. For 1.8
Myr the lifestyle of hunter-gatherers (HGs) comprised intense physical activity and a high …

Obesity, primarily characterized by excessive fat accumulation, is a multifactorial chronic
disease with an increasing global prevalence. Despite the well-documented epidemiology …

Obesity is a common, serious, and costly disease. More than 1 billion people worldwide are
obese—650 million adults, 340 million adolescents, and 39 million children. The WHO …

The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

Obesity-associated insulin resistance is a major risk factor for type 2 diabetes and
cardiovascular disease. In the past decade, a large number of endocrine, inflammatory …

The prevalence of obesity, which is a heritable trait that arises from the interactions of
multiple genes and lifestyle factors, continues to increase worldwide, causing serious health …

Now recognized as more than just the result of overeating or the consumption of poor-quality
foods, obesity is understood to be a multifactorial disease, strongly correlated with a variety …

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The recent increase in the worldwide prevalence of obesity has understandably focused
attention on the environmental determinants of this epidemic. Whereas identifying the …