The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation

EJ Kim, N Kim, SG Cho - Experimental & molecular medicine, 2013 - nature.com
In the last 10 years, mesenchymal stem cells (MSCs) have emerged as a therapeutic
approach to regenerative medicine, cancer, autoimmune diseases, and many more due to …

The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases

E Ben-Ami, S Berrih-Aknin, A Miller - Autoimmunity reviews, 2011 - Elsevier
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent progenitor cells which
can be isolated from various human adult tissues. In recent years, MSCs have been shown …

Mechanisms of immune modulation by mesenchymal stromal cells and clinical translation

J Stagg, J Galipeau - Current molecular medicine, 2013 - ingentaconnect.com
Cell therapy with mesenchymal stromal cells (MSCs) is the focus of intensive investigation.
Several clinical trials, including large-scale placebo-controlled phase III clinical trials, are …

Mesenchymal stem cells in homeostasis and systemic diseases: hypothesis, evidences, and therapeutic opportunities

FJ Vizoso, N Eiro, L Costa, P Esparza… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known
function in tissue regeneration. However, there is also evidence indicating a broader role of …

Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases

CR Harrell, N Jovicic, V Djonov, N Arsenijevic… - Cells, 2019 - mdpi.com
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …

Unraveling the mesenchymal stromal cells' paracrine immunomodulatory effects

MJ Fontaine, H Shih, R Schäfer, MF Pittenger - Transfusion medicine …, 2016 - Elsevier
In the last 10 years, the role of mesenchymal stromal cells (MSCs) in modulating
inflammatory and immune responses has been characterized using both in vitro studies and …

[PDF][PDF] Mesenchymal stromal cells: new directions

A Keating - Cell stem cell, 2012 - cell.com
Research into mesenchymal stromal/stem cells (MSCs) has been particularly exciting in the
past five years. Our understanding of mechanisms of MSC-mediated tissue regeneration has …

[HTML][HTML] New strategies for overcoming limitations of mesenchymal stem cell-based immune modulation

N Kim, SG Cho - International journal of stem cells, 2015 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have rapidly been applied in a broad field of immune-
mediated disorders since the first successful clinical use of MSCs for treatment of graft …

The immunomodulatory potential of mesenchymal stromal cells: a story of a regulatory network

M Najar, G Raicevic, E Crompot… - Journal of …, 2016 - journals.lww.com
Mesenchymal stromal cells (MSCs) have recently been the subject of great interest in the
fields of regenerative medicine and immunotherapy due to their unique biological …