The SARS-CoV-2 virus causes severe respiratory failure due in large part to viral tropism for
the ACE2 protein on the surface of alveolar epithelial and vascular endothelial cells …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …

Vaccination is proven to be effective in controlling many infections including small pox,
influenza and hepatitis, but strain-specific factors may limit vaccine efficacy. All of these …

SARS-CoV-2 infection is characterized by peak viral load in the upper airway prior to or at
the time of symptom onset, an unusual feature that has enabled widespread transmission of …

The COVID-19 pandemic, caused by the highly transmissible and pathogenic severe acute
respiratory syndrome coronavirus 2 (SAR-CoV-2), has led to more than 2.7 million deaths …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern have
emerged and may pose a threat to both the efficacy of vaccines based on the original …

Abstract Background Coronavirus Disease 2019 (Covid-19) continues to challenge the limits
of our knowledge and our healthcare system. Here we sought to define the host immune …

Occasional zoonotic viral attacks on immunologically naive populations result in massive
death tolls that are capable of threatening human survival. Currently, severe acute …

In the year since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) and with understanding of the etiology of the coronavirus disease 2019 (COVID-19) …