Stretching and electrical stimulation regulate the metalloproteinase-2 in rat denervated skeletal muscle

SM Peviani, TL Russo, JLQ Durigan… - Neurological …, 2010 - Taylor & Francis
Objective: To evaluate the effects of electrical stimulation (ES), stretching and their combined
effects in matrix metalloproteinases (MMPs) gene expression and activity during early …

Electrical stimulation increases matrix metalloproteinase‐2 gene expression but does not change its activity in denervated rat muscle

TL Russo, SM Peviani, JLQ Durigan… - Muscle & Nerve …, 2008 - Wiley Online Library
Muscle‐fiber atrophy occurs concomitantly with intramuscular connective tissue proliferation
following denervation. These events contribute to the impairment of mechanical and …

Matrix metalloproteinases MMP-2, MMP-7 and MMP-9 in denervated human muscle

BGH Schoser, D Blottner - Neuroreport, 1999 - journals.lww.com
PROTEOLYTIC enzyme expression was studied by matrix metalloproteinases (MMP)
immunoreactivity (-IR) in muscle biopsies from patients with amyotrophic lateral sclerosis …

Characterization of matrix metalloproteinases in denervated muscle

M Demestre, M Orth, GM Wells… - Neuropathology and …, 2005 - Wiley Online Library
In a nerve crush model of denervation, we examined muscle matrix metalloproteinase
(MMP) expression, localization and activity. In normal muscle, MMP mRNA levels were low …

MMP-2 is not altered by stretching in skeletal muscle

SM Peviani, ARS Gomes… - … journal of sports …, 2009 - thieme-connect.com
Considering that short bouts of stretching, as recommended in rehabilitation and sports
activities, induce skeletal muscle and connective tissue adaptation, the hypothesis of this …

Regulation of connective tissue remodeling in the early phase of denervation in a rat skeletal muscle

J Ozawa, T Kurose, S Kawamata, A Kaneguchi… - Biomedical …, 2013 - jstage.jst.go.jp
Denervation alters the metabolism of the extracellular matrix (ECM) in skeletal muscle;
however, the underlying mechanisms of ECM remodeling are not fully understood. The aim …

Intermittent stretching induces fibrosis in denervated rat muscle

FM Faturi, RC Franco, D Gigo‐Benato, AC Turi… - Muscle & …, 2016 - Wiley Online Library
ABSTRACT Introduction: Stretching (St) has been used for treating denervated muscles.
However, its effectiveness and safety claims require further study. Methods: Rats were …

High intensity exercise increases expression of matrix metalloproteinases in fast skeletal muscle fibres

E Carmeli, M Moas, S Lennon… - Experimental …, 2005 - Wiley Online Library
Metalloproteinases (MMPs) are proteolytic enzymes that function in the extracellular matrix
to degrade connective tissues. While it is clear that exercise‐induced injury in skeletal …

Resistance exercise increases active MMP and β1‐integrin protein expression in skeletal muscle

R Ogasawara, K Nakazato, K Sato… - Physiological …, 2014 - Wiley Online Library
Recent studies indicate that matrix metalloproteinases (MMP s) and critical linkage proteins
in the extracellular matrix (ECM) regulate skeletal muscle mass, although the effects of …

[HTML][HTML] Matrix metalloproteinase-2 plays a critical role in overload induced skeletal muscle hypertrophy

Q Zhang, SK Joshi, DH Lovett, B Zhang… - … and tendons journal, 2014 - ncbi.nlm.nih.gov
Background: extracellular matrix (ECM) components are instrumental in maintaining
homeostasis and muscle fiber functional integrity. Skeletal muscle hypertrophy is associated …