[PDF][PDF] Assessment of the potential of plasma fractionation processes to remove causative agents of transmissible spongiform encephalopathy

PR Foster - Transfusion Medicine, 1999 - infectedbloodinquiry.org.uk
Although there is no evidence that classical CJD (cCJD) can be transmitted by human blood
or blood products in clinical practice, uncertainties surrounding new variant CJD (nvCJD) …

Current strategies to prevent transmission of prions by human plasma derivatives

T Burnouf, A Padilla - Transfusion clinique et biologique, 2006 - Elsevier
Protein products prepared from pooled human plasma are an essential class of therapeutics
used mostly to control bleeding and/or immunological disorders. Because of the human …

Manufacture of plasma-derived products in France and measures to prevent the risk of vCJD transmission: precautionary measures and efficacy of manufacturing …

B Flan, S Arrabal - Transfusion clinique et biologique, 2007 - Elsevier
The emergence of the variant Creutzfeldt-Jakob disease in the mid 1990s soon raised
concerns about its possible transmission through the use of blood and plasma-derived …

The risk of transmitting prion disease by blood or plasma products

R Knight - Transfusion and Apheresis Science, 2010 - Elsevier
Various experimental studies have shown infectivity in blood in relation to bovine
spongiform encephalitis (BSE) and variant Creutzfeldt–Jakob disease (vCJD). Human to …

Variant Creutzfeldt–Jakob disease transmission by plasma products: assessing and communicating risk in an era of scientific uncertainty

A Farrugia, JW Ironside, P Giangrande - Vox sanguinis, 2005 - Wiley Online Library
A substantial body of animal data indicates that transmissible spongiform encephalopathies
(TSEs) are transmitted through blood. These data have been augmented in the past year by …

An overview of prion biology and the role of blood filtration in reducing the risk of transfusion-transmitted variant Creutzfeldt-Jakob disease

JS Cervia, SO Sowemimo-Coker, GA Ortolano… - Transfusion Medicine …, 2006 - Elsevier
Prions are infectious proteins believed to be responsible for a variety of progressive and
fatal neurodegenerative diseases, collectively referred to as transmissible spongiform …

A report on transmissible spongiform encephalopathies and transfusion safety

J Coste, C Prowse, R Eglin, C Fang… - Vox …, 2009 - Wiley Online Library
The incidence of BSE in Europe is in continued decline. At present, iatrogenic transmission
from person to person is considered a serious threat to public health. This report of the …

[图书][B] WHO guidelines on tissue infectivity distribution in transmissible spongiform encephalopathies

World Health Organization - 2006 - apps.who.int
EXECUTIVE SUMMARY A variant form of Creutzfeldt-Jakob Disease (vCJD), a fatal brain
disease of humans, first appeared in the mid-1990s, as a result of the bovine spongiform …

An update on the assessment and management of the risk of transmission of variant Creutzfeldt‐Jakob disease by blood and plasma products

ML Turner, CA Ludlam - British journal of haematology, 2009 - Wiley Online Library
There have been four highly probable instances of variant Creutzfeldt‐Jakob disease
(vCJD) transmission by non‐leucocyte depleted red cell concentrates and it is now clear that …

[引用][C] Prion disease and blood transfusion

P FLANAGAN, JAJ BARBARA - Transfusion Medicine, 1996 - Wiley Online Library
This edition of Transfusion Medicine contains an article by S. Dealler outlining his personal
assessment of the potential risk of bovine spongiform encephalopathy (BSE) to humans …