[HTML][HTML] Congenital viral infections of the brain: lessons learned from lymphocytic choriomeningitis virus in the neonatal rat

DJ Bonthius, S Perlman - PLoS pathogens, 2007 - journals.plos.org
The fetal brain is highly vulnerable to teratogens, including many infectious agents. As a
consequence of prenatal infection, many children suffer severe and permanent brain injury …

Lymphocytic choriomeningitis virus infection of the developing brain: critical role of host age

DJ Bonthius, B Nichols, H Harb, J Mahoney… - Annals of …, 2007 - Wiley Online Library
Objective Lymphocytic choriomeningitis virus (LCMV) is a common human pathogen that
causes substantial injury to the developing brain when the infection occurs during …

Altered central nervous system gene expression caused by congenitally acquired persistent infection with lymphocytic choriomeningitis virus

S Kunz, JM Rojek, AJ Roberts, DB McGavern… - Journal of …, 2006 - Am Soc Microbiol
Neonatal infection of most mouse strains with lymphocytic choriomeningitis virus (LCMV)
leads to a life-long persistent infection characterized by high virus loads in the central …

Critical role for glial cells in the propagation and spread of lymphocytic choriomeningitis virus in the developing rat brain

DJ Bonthius, J Mahoney, MJ Buchmeier… - Journal of …, 2002 - Am Soc Microbiol
Inoculation of the neonatal rat with lymphocytic choriomeningitis virus (LCMV) results in the
selective infection of several neuronal populations and in focal pathological changes …

Lymphocytic choriomeningitis virus: an underrecognized cause of neurologic disease in the fetus, child, and adult

DJ Bonthius - Seminars in pediatric neurology, 2012 - Elsevier
Lymphocytic choriomeningitis virus (LCMV) is an important cause of neurologic disease in
humans. Carried and secreted principally by wild mice, LCMV covers a large geographic …

[HTML][HTML] Lymphocytic choriomeningitis infection of the central nervous system

SS Kang, DB McGavern - Frontiers in bioscience: a journal and …, 2008 - ncbi.nlm.nih.gov
Viral infection of the central nervous system (CNS) can result in a multitude of responses
including pathology, persistence or immune clearance. Lymphocytic choriomeningitis virus …

Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniation

CM Matullo, KJ O'Regan, H Hensley, M Curtis… - Journal of …, 2010 - Am Soc Microbiol
Although much is known about lymphocytic choriomeningitis virus (LCMV) infection and the
subsequent immune response in its natural murine host, some crucial aspects of LCMV …

Lymphocytic choriomeningitis virus: a prenatal and postnatal threat

DJ Bonthius - Advances in pediatrics, 2009 - advancesinpediatrics.com
LCMV is an important cause of meningitis in children and adults, and of encephalopathy and
neurologic birth defects in newborns. Acquired and congenital LCMV infections are …

Congenital lymphocytic choriomeningitis virus infection: spectrum of disease

DJ Bonthius, R Wright, B Tseng, L Barton… - Annals of …, 2007 - Wiley Online Library
Objective Lymphocytic choriomeningitis virus (LCMV) is a human pathogen and an
emerging neuroteratogen. When the infection occurs during pregnancy, the virus can target …

Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons

JC De la Torre, G Rall, C Oldstone, PP Sanna… - Journal of …, 1993 - Am Soc Microbiol
We have investigated the replication of lymphocytic choriomeningitis virus (LCMV) before
and after the nerve growth factor (NGF)-induced transdifferentiation of PC12 cells from the …