Changes in cell morphology due to plasma membrane wounding by acoustic cavitation

RK Schlicher, JD Hutcheson, H Radhakrishna… - Ultrasound in medicine …, 2010 - Elsevier
Acoustic cavitation-mediated wounding (ie, sonoporation) has great potential to improve
medical and laboratory applications requiring intracellular uptake of exogenous molecules; …

Mechanism of intracellular delivery by acoustic cavitation

RK Schlicher, H Radhakrishna, TP Tolentino… - Ultrasound in medicine …, 2006 - Elsevier
Using conditions different from conventional medical imaging or laboratory cell lysis,
ultrasound has recently been shown to reversibly increase plasma membrane permeability …

Ultrasound-mediated disruption of cell membranes. II. Heterogeneous effects on cells

HR Guzman, DX Nguyen, S Khan… - The Journal of the …, 2001 - pubs.aip.org
Ultrasound has been shown to reversibly and irreversibly disrupt membranes of viable cells
through a mechanism believed to involve cavitation. Because cavitation is both temporally …

Transendothelial perforations and the sphere of influence of single-site sonoporation

B Helfield, X Chen, SC Watkins… - Ultrasound in medicine & …, 2020 - Elsevier
Acoustically driven gas bubble cavitation locally concentrates energy and can result in
physical phenomena including sonoluminescence and erosion. In biomedicine, ultrasound …

Sonoluminescence as an indicator of cell membrane disruption by acoustic cavitation

SA Cochran, MR Prausnitz - Ultrasound in medicine & biology, 2001 - Elsevier
Ultrasound (US) has been shown to transiently disrupt cell membranes and, thereby,
facilitate the loading of drugs and genes into viable cells. Because these effects are believed …

[HTML][HTML] Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors

CH YuAlfred - BME frontiers, 2022 - spj.science.org
Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …

Bioeffects caused by changes in acoustic cavitation bubble density and cell concentration: a unified explanation based on cell-to-bubble ratio and blast radius

HR Guzmán, AJ McNamara, DX Nguyen… - Ultrasound in medicine …, 2003 - Elsevier
Acoustic cavitation has been shown to load drugs, proteins and DNA into viable cells as a
complex function of acoustic and nonacoustic parameters. To better understand and quantify …

Controlled permeation of cell membrane by single bubble acoustic cavitation

Y Zhou, K Yang, J Cui, JY Ye, CX Deng - Journal of controlled release, 2012 - Elsevier
Sonoporation is the membrane disruption generated by ultrasound and has been exploited
as a non-viral strategy for drug and gene delivery. Acoustic cavitation of microbubbles has …

Measurement and correlation of acoustic cavitation with cellular bioeffects

DM Hallow, AD Mahajan, TE McCutchen… - Ultrasound in medicine …, 2006 - Elsevier
Using broadband noise as a measure of cavitation activity, this study determined the kinetics
of cavitation during sonication of Optison® contrast agent and tested whether cellular …

Cell size relations for sonolysis

MW Miller - Ultrasound in medicine & biology, 2004 - Elsevier
The occurrence of cell lysis following exposure to ultrasound (US) has been well
documented; the specifics of the mechanistic process (es) involved have proven to be …