[HTML][HTML] Isolation, sequence, infectivity, and replication kinetics of severe acute respiratory syndrome coronavirus 2

A Banerjee, JA Nasir, P Budylowski, L Yip… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Since its emergence in Wuhan, China, in December 2019, severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has infected≈ 6 million persons worldwide. As …

[HTML][HTML] Characterisation of vaccine breakthrough infections of SARS-CoV-2 Delta and Alpha variants and within-host viral load dynamics in the community, France …

F Blanquart, C Abad, J Ambroise, M Bernard… - …, 2021 - eurosurveillance.org
We compared PCR results from SARS-CoV-2-positive patients tested in the community in
France from 14 June to 30 July 2021. In asymptomatic individuals, Cq values were …

The total number and mass of SARS-CoV-2 virions

R Sender, YM Bar-On, S Gleizer… - Proceedings of the …, 2021 - National Acad Sciences
Quantitatively describing the time course of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …

[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …

Twin peaks: the Omicron SARS-CoV-2 BA. 1 and BA. 2 epidemics in England

P Elliott, O Eales, N Steyn, D Tang, B Bodinier, H Wang… - Science, 2022 - science.org
Rapid transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Omicron variant has led to record-breaking incidence rates around the world. The Real-time …

Predicting infectivity: comparing four PCR‐based assays to detect culturable SARS‐CoV‐2 in clinical samples

EA Bruce, MG Mills, R Sampoleo… - EMBO Molecular …, 2022 - embopress.org
With the COVID‐19 pandemic caused by SARS‐CoV‐2 now in its second year, there
remains an urgent need for diagnostic testing that can identify infected individuals …

Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness

R Ke, PP Martinez, RL Smith, LL Gibson, A Mirza… - Nature …, 2022 - nature.com
The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly
understood. We captured the dynamics of infectious virus and viral RNA shedding during …

Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated individuals

SM Kissler, JR Fauver, C Mack, CG Tai, MI Breban… - MedRxiv, 2021 - medrxiv.org
We estimated (1) the time from first detectable virus to peak viral concentration (proliferation
time),(2) the time from peak viral concentration to initial return to the limit of detection …

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

JJA van Kampen, DAMC van de Vijver… - Nature …, 2021 - nature.com
Key questions in COVID-19 are the duration and determinants of infectious virus shedding.
Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 …

Networks of SARS-CoV-2 transmission

M Cevik, SD Baral - Science, 2021 - science.org
The basic reproduction number, R 0 (the number of infections caused by a case in a
homogeneously susceptible population), for a particular infection is dependent on the …