In order to improve active tumor targeting, tumor cell uptake efficiency and circulation time of
doxorubicin (DOX) in vivo, we constructed a cleavable PEGylated hyaluronic acid nano-drug …

Two kinds of reduction and pH responsive disulfide-cross-linked poly (ethylene glycol)-
polypeptide copolymers were prepared through one-step ring-opening polymerization of γ …

Abstract pH-Responsive nanoparticles (NPs) have emerged as an effective antitumor drug
delivery system, promoting the drugs accumulation in the tumor and selectively releasing …

Tumor targetability and site-specific drug release of therapeutic nanoparticles are key factors
for effective cancer therapy. In this study, poly (ethylene glycol)(PEG)-conjugated hyaluronic …

Hydrogel as a local drug depot can increase drug concentration at the tumor site. However,
conventional drug-loaded hydrogel is typically formed by direct dissolution of drug …

Nanodrug‐based cancer therapy is impeded by poor penetration into deep tumor tissues
mainly due to the overexpression of hyaluronic acid (HA) in the tumor extracellular matrix …

For the treatment of malignant tumors, drug nanocarriers with long blood circulation time and
ability to target the tumor microenvironment are promising therapeutic abilities. In this work …

To achieve effective intracellular anticancer drug release for boosted antitumor efficacy, the
acidity-responsive nanovehicles for doxorubicin (DOX) delivery were fabricated by tailor …

Hyaluronic acid (HA) is a natural ligand of tumor-targeted drug delivery systems (DDS) due
to the relevant CD44 receptor overexpressed on tumor cell membranes. However, other HA …

Hyaluronic acid (HA)-based theranostic nanogels were designed for the tumor diagnosis
and chemotherapy, by crosslinking the folate-terminated poly (ethylene glycol) modified …