Cellular immune responses in amniotic fluid of women with preterm labor and intra‐amniotic infection or intra‐amniotic inflammation

N Gomez‐Lopez, R Romero, J Galaz… - American Journal of …, 2019 - Wiley Online Library
Problem Preterm birth is commonly preceded by preterm labor, a syndrome that is causally
linked to both intra‐amniotic infection and intra‐amniotic inflammation. However, the …

Evidence of perturbations of the cytokine network in preterm labor

R Romero, JC Grivel, AL Tarca… - American journal of …, 2015 - Elsevier
Objective Intraamniotic inflammation/infection is the only mechanism of disease with
persuasive evidence of causality for spontaneous preterm labor/delivery. Previous studies …

Interleukin-6 concentrations in cervical secretions identify microbial invasion of the amniotic cavity in patients with preterm labor and intact membranes

G Rizzo, A Capponi, D Rinaldo, D Tedeschi… - American journal of …, 1996 - Elsevier
OBJECTIVE: The objectives of this study were to determine whether cytokine levels in
cervical secretions were increased in the presence of microbial invasion of the amniotic …

Interleukin 16 in pregnancy, parturition, rupture of fetal membranes, and microbial invasion of the amniotic cavity

N Athayde, R Romero, E Maymon, R Gomez… - American journal of …, 2000 - Elsevier
Objective: Interleukin 16 is a proinflammatory cytokine that promotes the recruitment of
nonclonotypic T cells and eosinophils to sites of inflammation and induces resistance to …

Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-α in normal pregnancies and in pregnancies complicated by …

M Tosun, H Celik, B Avci, E Yavuz, T Alper… - The Journal of …, 2010 - Taylor & Francis
Objectives. The aim of this study was to investigate the relationship of maternal and
umbilical cord interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α) serum …

Inflammation in preterm and term labour and delivery

R Romero, J Espinoza, LF Gonçalves… - Seminars in Fetal and …, 2006 - Elsevier
Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and …

Preeclamptic women are deficient of interleukin-10 as assessed by cytokine release of trophoblast cells in vitro

DT Rein, M Breidenbach, B Hönscheid… - Cytokine, 2003 - Elsevier
Background: It is well known that the acceptance of the fetoplacental unit in human
pregnancy requires maternal immune tolerance, which is thought to be regulated locally by …

Pro‐inflammatory maternal cytokine profile in preterm delivery

M Makhseed, R Raghupathy… - American journal of …, 2003 - Wiley Online Library
PROBLEM: The objective of this study was to determine the levels of cytokines produced by
maternal peripheral blood mononuclear cells (PBMC) upon stimulation with a mitogen, with …

Macrophage inflammatory protein‐1α in term and preterm parturtition: Effect of microbial invasion of the amniotic cavity

R Romero, R Gomez, M Galasso… - American Journal of …, 1994 - Wiley Online Library
PROBLEM: This study was conducted to determine whether:(1) gestational age, parturition,
and microbial invasion of the amniotic cavity (MIAC) are associated with changes in amniotic …

Inflammatory mediators in umbilical plasma from neonates who develop early-onset sepsis

H Døllner, L Vatten, I Linnebo, GF Zanussi, Å Lærdal… - Neonatology, 2001 - karger.com
Objectives: To study whether early-onset neonatal sepsis is associated with a prenatal
immune response with elevated umbilical plasma levels of inflammatory mediators, and to …