Fragile X is the most common monogenic disorder associated with intellectual disability (ID)
and autism spectrum disorders (ASD). Additionally, many patients are afflicted with …

Fragile X syndrome (FX), the most common heritable cause of mental retardation and
autism, is a developmental disorder characterized by physical, cognitive, and behavioral …

Fragile X syndrome (FXS) is the leading cause of inherited intellectual disability, with
additional symptoms including attention deficit and hyperactivity, anxiety, impulsivity, and …

Fragile X syndrome (FXS) is the most common identifiable genetic cause of intellectual
disability and autistic spectrum disorders (ASD), with up to 50% of males and some females …

Fragile X syndrome (FXS) is the leading cause of both intellectual disability and autism
resulting from a single gene mutation. Previously, we characterized cognitive impairments …

Fragile-X syndrome (FXS) patients display intellectual disability and autism spectrum
disorder due to silencing of the X-linked, fragile-X mental retardation-1 (FMR1) gene …

Fragile X syndrome, caused by the loss of Fmr1 gene function, is the most common form of
inherited mental retardation, with no effective treatment. Using a tractable animal model, we …

Abstract Background Fragile X syndrome (FXS) is the most common identifiable genetic
cause of intellectual disability and autistic spectrum disorders. Recent major advances have …

Background Fragile X syndrome (FXS) is the most common genetic cause for intellectual
disability. Fmr1 knockout (KO) mice are an established model of FXS. Chronic …

Loss of the RNA-binding fragile X protein [fragile X mental retardation protein (FMRP)]
results in a spectrum of cognitive deficits, the fragile X syndrome (FXS), while aging …