Clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma

H Sihto, H Kukko, V Koljonen, R Sankila… - JNCI: Journal of the …, 2009 - academic.oup.com
Background Merkel cell carcinoma is a rare malignancy of the skin. Integration of Merkel cell
polyomavirus (MCPyV) DNA to the tumor genome is frequent in these cancers. The clinical …

Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma

H Sihto, H Kukko, V Koljonen, R Sankila, T Böhling… - Clinical Cancer …, 2011 - AACR
Purpose: Merkel cell carcinoma (MCC) is rare skin cancer that is often associated with
Merkel cell polyomavirus (MCPyV) infection. Polyomaviruses repress tumor suppressor …

Prevalence of MCPyV in Merkel cell carcinoma and non‐MCC tumors

C Andres, B Belloni, U Puchta… - Journal of cutaneous …, 2010 - Wiley Online Library
Background: Merkel cell polyomavirus (MCPyV) is the likely causative agent of Merkel cell
carcinoma (MCC). However, the prevalence of MCPyV in non‐MCC population and its …

[HTML][HTML] Genetic variability and integration of Merkel cell polyomavirus in Merkel cell carcinoma

C Martel-Jantin, C Filippone, O Cassar, M Peter… - Virology, 2012 - Elsevier
Merkel cell polyomavirus (MCPyV) is associated to Merkel cell carcinoma (MCC). We
studied 113 MCC tumoral skin lesions originating from 97 patients. MCPyV detection was …

High levels of antibodies against merkel cell polyomavirus identify a subset of patients with merkel cell carcinoma with better clinical outcome

A Touzé, E Le Bidre, H Laude, MJJ Fleury… - Journal of Clinical …, 2011 - ascopubs.org
Purpose A new human polyomavirus, Merkel cell polyomavirus (MCV), was identified in
2008 in tumor tissue of patients with Merkel cell carcinoma (MCC), a relatively rare human …

[HTML][HTML] Inflammatory monocytes are a reservoir for Merkel cell polyomavirus

KD Mertz, T Junt, M Schmid, M Pfaltz… - Journal of Investigative …, 2010 - Elsevier
Merkel cell polyomavirus (MCPyV) is a recently discovered virus that is implicated in the
oncogenesis of Merkel cell carcinoma (MCC). The route of dissemination and the reservoir …

Epidemiology of Merkel cell polyomavirus infection and Merkel cell carcinoma

S Silling, A Kreuter, T Gambichler, T Meyer… - Cancers, 2022 - mdpi.com
Simple Summary Merkel cell polyomavirus (MCPyV) is a widespread virus that is present on
human skin. Infection occurs early in life, and up to 90% of adults have antibodies against …

Merkel cell polyomavirus DNA detection in lesional and nonlesional skin from patients with Merkel cell carcinoma or other skin diseases

V Foulongne, O Dereure, N Kluger… - British Journal of …, 2010 - academic.oup.com
Background A novel polyomavirus, the Merkel cell polyomavirus (MCPyV), has recently
been identified in Merkel cell carcinoma (MCC). Objectives To investigate the specificity of …

Association of Merkel cell polyomavirus infection with tumor p53, KIT, stem cell factor, PDGFR‐alpha and survival in Merkel cell carcinoma

M Waltari, H Sihto, H Kukko, V Koljonen… - … Journal of Cancer, 2011 - Wiley Online Library
Abstract Most Merkel cell carcinomas (MCCs) contain Merkel cell polyomavirus (MCPyV)
DNA, and the virus likely has a pivotal role in tumor pathogenesis. p53 and the KIT receptor …

[HTML][HTML] Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma

D Schrama, WK Peitsch, M Zapatka, H Kneitz… - Journal of Investigative …, 2011 - Elsevier
The majority of Merkel cell carcinomas (MCCs) are associated with the recently identified
Merkel cell polyomavirus (MCV). However, as it is still unclear to which extent the presence …