Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein

T Haystead, E Lee, K Cho, G Gullickson, P Hughes… - Scientific Reports, 2023 - nature.com
Evidence in SARS-CoV-2 patients have identified that viral infection is accompanied by the
expression of inflammatory mediators by both immune and stromal cells within the …

SARS-CoV-2 nucleocapsid protein, rather than spike protein, triggers a cytokine storm originating from lung epithelial cells in patients with COVID-19

YC Wang, CH Tsai, YC Wang, LC Yen, YW Chang… - Infection, 2023 - Springer
Purpose The aim of this study was to elucidate the factors associated with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) that may initiate cytokine cascades and …

Stability of SARS-CoV-2-Encoded Proteins and Their Antibody Levels Correlate with Interleukin 6 in COVID-19 Patients

W Li, GD Kitsios, W Bain, C Wang, T Li, KV Fanning… - Msystems, 2022 - Am Soc Microbiol
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of coronavirus disease 2019 (COVID-19), has become a severe global …

Multifaceted role of SARS-CoV-2 structural proteins in lung injury

G Zheng, G Qiu, H Qian, Q Shu, J Xu - Frontiers in Immunology, 2024 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third human
coronavirus to cause acute respiratory distress syndrome (ARDS) and contains four …

study of the effects of several SARS-CoV-2 structural proteins on antiviral immunity

R Yue, F Zeng, D Ma, Z Meng, X Li, Z Zhang, H Zhang… - Vaccines, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike (S) protein is a
critical viral antigenic protein that enables the production of neutralizing antibodies, while …

Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases

S Kakavandi, I Zare, M VaezJalali, M Dadashi… - Cell Communication and …, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …

SARS-CoV-2 spike protein activates human lung macrophages

F Palestra, R Poto, R Ciardi, G Opromolla… - International Journal of …, 2023 - mdpi.com
COVID-19 is a viral disease caused by SARS-CoV-2. This disease is characterized
primarily, but not exclusively, by respiratory tract inflammation. SARS-CoV-2 infection relies …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Deciphering SARS-CoV-2 virologic and immunologic features

G Lebeau, D Vagner, E Frumence, F Ah-Pine… - International journal of …, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 and its associated
pathology, COVID-19, have been of particular concerns these last months due to the …

SARS-CoV-2 recombinant proteins stimulate distinct cellular and humoral immune response profiles in samples from COVID-19 convalescent patients

LT Silva, MM Ortega, BT Tiyo, IFT Viana, TE Lima… - Clinics, 2021 - SciELO Brasil
OBJECTIVES: In this preliminary study we investigated cellular and humoral immune
responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens in …